Induction of strong hepatitis B virus (HBV) specific T helper cell and cytotoxic T lymphocyte responses by therapeutic vaccination in the trimera mouse model of chronic HBV infection

Humanized BALB / c mice (termed trimera mice) conditioned by lethal total body irradiation and bone marrow transplantation from SCID mice have been described to support rapid engraftment of human peripheral blood mononuclear cells (PBMC) and the induction of strong B and T cell responses after immun...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of immunology 2001-07, Vol.31 (7), p.2071-2079
Hauptverfasser:	Böcher, Wulf O., Dekel, Benjamin, Schwerin, Wibke, Geissler, Michael, Hoffmann, Sina, Rohwer, Andreas, Arditti, Fabian, Cooper, Aric, Bernhard, Helga, Berrebi, Alain, Rose‐John, Stefan, Shaul, Yosef, Galle, Peter R., Löhr, Hanns F., Reisner, Yair
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens - immunology Borrelia burgdorferi Cells, Cultured Dendritic Cells - transplantation Disease Models, Animal Hepatitis B Antibodies - biosynthesis Hepatitis B Core Antigens - immunology Hepatitis B Vaccines - pharmacology Hepatitis B virus Hepatitis B virus - immunology Hepatitis B, Chronic - immunology Hepatitis B, Chronic - therapy Humans Immunotherapy Interferon-gamma - biosynthesis Leukocytes, Mononuclear - transplantation Mice Mice, Inbred BALB C Mice, SCID T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Helper-Inducer - immunology Trimera mouse model Vaccines, DNA - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!