First identification of an SHV-12 extended-spectrum β-lactamase in Klebsiella pneumoniae isolated in Italy

A clinical isolate of Klebsiella pneumoniae highly resistant to third- and fourth-generation cephalosporins, cephamycins and aminoglycosides, was isolated in 1991 from urine. Analysis of a crude extract showed the presence of three beta-lactamases with isoelectric points of 6.6, 7.5 and 8.2. The enz...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2000-03, Vol.45 (3), p.349-351
Hauptverfasser:	LAKSAI, Y, SEVERINO, M, PERILLI, M, AMICOSANTE, G, BONFIGLIO, G, STEFANI, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteriology beta-Lactamases - analysis beta-Lactamases - genetics beta-Lactamases - isolation & purification Biological and medical sciences Conjugation, Genetic DNA, Bacterial - genetics DNA, Bacterial - isolation & purification Drug Resistance, Microbial Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Humans Italy Klebsiella Infections - microbiology Klebsiella pneumoniae Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - genetics Medical sciences Metabolism. Enzymes Microbial Sensitivity Tests Microbiology Pharmacology. Drug treatments Plasmids - genetics SHV-12
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