Three-dimensional Structure of Ryanodine Receptor Isoform Three in Two Conformational States as Visualized by Cryo-electron Microscopy

Using cryo-electron microscopy and single particle image processing techniques, we present the first three-dimensional reconstructions of isoform 3 of the ryanodine receptor/calcium release channel (RyR3). Reconstructions were carried out on images obtained from a purified, detergent-solubilized rec...

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Veröffentlicht in:	The Journal of biological chemistry 2000-03, Vol.275 (13), p.9485-9491
Hauptverfasser:	Sharma, Manjuli R., Jeyakumar, Loice H., Fleischer, Sidney, Wagenknecht, Terence
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Buffers Cattle Cryoelectron Microscopy Models, Molecular Protein Conformation Protein Isoforms - chemistry Protein Isoforms - ultrastructure Ryanodine Receptor Calcium Release Channel - chemistry Ryanodine Receptor Calcium Release Channel - ultrastructure
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