Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats

In the present study, we investigated the effect of immediate post-training bilateral infusion of spermidine, a polyamine agonist, into the amygdala on inhibitory avoidance learning of rats. Bilateral microinjection of spermidine (0.02–20 nmol) caused an increase in test step-down latencies at high...

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Veröffentlicht in:	European journal of pharmacology 2001-06, Vol.423 (1), p.35-39
Hauptverfasser:	Rubin, Maribel A, Stiegemeier, Juliano A, Volkweis, Márcio A, Oliveira, Denise M, Fenili, Ana C, Boemo, Rafael L, Jurach, Alexandre, Mello, Carlos F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Amygdala - drug effects Animal Animals Arcaine Avoidance Learning - drug effects Behavior, Animal - drug effects Biguanides - pharmacology Biological and medical sciences Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Learning Learning. Memory Male Memory Motor Activity - drug effects Polyamine Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Wistar Spermidine Spermidine - pharmacology
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