Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo

The effects of administering reserpine (0.1 mg/kg) or 17α-ethinyloestradiol (2.5 mg/kg) to New Zealand White rabbits on low density lipoprotein receptors in liver, on plasma low density lipoprotein and fibrinogen and on plasma and tissue lipids were determined. Blood pressure and heart rate were als...

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Veröffentlicht in:	Atherosclerosis 2000-04, Vol.149 (2), p.267-275
Hauptverfasser:	Shafi, Shahida, Stepanova, Irina P, Fitzsimmons, C, Bowyer, D.E, Welzel, D, Born, G.V.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteriosclerosis - prevention & control Atherosclerosis Biological and medical sciences Cardiovascular system Cholesterol and arterial walls Culture Techniques Disease Models, Animal Ethinyl Estradiol - administration & dosage Fibrinogen - drug effects Fibrinogen - metabolism Hemodynamics - drug effects Hemodynamics - physiology Hepatic LDL receptor Injections, Subcutaneous Lipoproteins, LDL - blood Lipoproteins, LDL - drug effects Liver - drug effects Liver - metabolism Male Medical sciences Pharmacology. Drug treatments Rabbits Receptors, LDL - blood Receptors, LDL - drug effects Reference Values Reserpine Reserpine - administration & dosage Sensitivity and Specificity Vascular wall
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