Migration and Multipotentiality of PSA-NCAM+ Neural Precursors Transplanted in the Developing Brain

By optimizing the previously described strategy for obtention of spheres enriched in PSA-NCAM+ precursors, we prepared PSA-NCAM-immunoselected cell populations from cerebral hemispheres of neonatal MBP-LacZ transgenic mice. These cells expressed Nestin, exhibited clonal expansion potential and forme...

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Veröffentlicht in:	Molecular and cellular neuroscience 2001-06, Vol.17 (6), p.983-1000
Hauptverfasser:	Vitry, Sandrine, Avellana-Adalid, Virginia, Lachapelle, François, Baron-Van Evercooren, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - metabolism Astrocytes - cytology Astrocytes - metabolism Brain - cytology Brain - growth & development Brain - metabolism Brain Tissue Transplantation - methods Cell Aggregation - genetics Cell Culture Techniques - methods Cell Differentiation - physiology Cell Lineage - physiology Cell Movement - physiology Cells, Cultured - cytology Cells, Cultured - drug effects Cells, Cultured - metabolism Central Nervous System Diseases - surgery Clone Cells - cytology Clone Cells - drug effects Clone Cells - metabolism Culture Media - pharmacology Gangliosides - metabolism Gene Expression Regulation, Developmental - physiology Glial Fibrillary Acidic Protein - metabolism Graft Survival - physiology Intermediate Filament Proteins - metabolism Mice Mice, Transgenic Nerve Tissue Proteins Nestin Neural Cell Adhesion Molecule L1 Neural Cell Adhesion Molecules - genetics Neural Cell Adhesion Molecules - metabolism Neurons - cytology Neurons - metabolism Neurons - transplantation Oligodendroglia - cytology Oligodendroglia - metabolism polysialylation Sialic Acids - genetics Sialic Acids - metabolism Stem Cell Transplantation Stem Cells - cytology Stem Cells - metabolism Thalamus - cytology Thalamus - growth & development Thalamus - surgery
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