Effect of the AT1-Receptor Antagonists Losartan, Irbesartan, and Telmisartan on Angiotensin II-Induced Facilitation of Sympathetic Neurotransmission in the Rat Mesenteric Artery

The effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II (Ang II)-induced facilitation of noradrenergic neurotransmission was investigated in the isolated rat mesenteric artery under isometric conditions. Electrical field stimulation (2, 4, and 8 Hz) caused...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2001-07, Vol.38 (1), p.141-148
Hauptverfasser:	Balt, Jippe C, Mathy, Marie-Jeanne, Nap, Alexander, Pfaffendorf, Martin, van Zwieten, Pieter A
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Antihypertensive agents Antihypertensive Agents - pharmacology Benzimidazoles - pharmacology Benzoates - pharmacology Biological and medical sciences Biphenyl Compounds - pharmacology Cardiovascular system Dose-Response Relationship, Drug Electric Stimulation Irbesartan Losartan - pharmacology Male Medical sciences Mesenteric Arteries - drug effects Mesenteric Arteries - physiology Pharmacology. Drug treatments Rats Rats, Wistar Receptor, Angiotensin, Type 1 Receptors, Angiotensin - physiology Sympathetic Nervous System - drug effects Sympathetic Nervous System - physiology Telmisartan Tetrazoles - pharmacology Vasoconstrictor Agents - pharmacology
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