Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress

Polychlorinated biphenyls (PCBs) induce drug metabolism that may lead to the bioactivation of PCBs themselves or alternatively may lead to oxidative events within the cell. The goal of the present study was to determine the influence of congeneric PCBs, selected as substrates for or inducers of drug...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical pharmacology 2001-08, Vol.62 (3), p.273-281
Hauptverfasser:	Twaroski, Timothy P., O’Brien, Michelle L., Robertson, Larry W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Female Glutathione Glutathione - metabolism Glutathione peroxidase Glutathione Peroxidase - metabolism Glutathione reductase Glutathione Reductase - metabolism Glutathione transferase Liver - drug effects Liver - enzymology Liver - metabolism Male Medical sciences Oxidative Stress - drug effects Polychlorinated biphenyls (PCBs) Polychlorinated Biphenyls - pharmacology Rats Rats, Sprague-Dawley Selenium Selenium - metabolism Solvents Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!