Identification of the precipitate in alkalinized solutions of mepivacaine and bupivacaine at 37 degrees C

Commercial and control solutions of bupivacaine (0(.)75%) and mepivacaine (1(.)5%) were alkalinized with bicarbonate until cloudy at room temperature. The solutions were heated to 37 degrees C for 2(.)5 h. The precipitates were filtered, lyophylized and analysed by fast atom bombardment mass spectro...

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Veröffentlicht in:	Journal of clinical pharmacy and therapeutics 2001-06, Vol.26 (3), p.171-173
Hauptverfasser:	Bigeleisen, P E, Wempe, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Local - chemistry Bupivacaine - chemistry Chemical Precipitation Hydrogen-Ion Concentration Mass Spectrometry Mepivacaine - chemistry Molecular Weight Sodium Bicarbonate - chemistry
Online-Zugang:	Volltext
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