Acute effects of interferon on estrogen receptor function do not involve the extracellular signal-regulated kinases p42mapk and p44mapk

Exposure to type I interferons (IFN) increased estrogen receptor (ER) ligand binding and induced protein kinase C (PKC) translocation within 30 min but had no effect on net incorporation of [32P] into ER in Madin Darby bovine kidney (MDBK) cells. Ligand binding was also increased within 30 min by ph...

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Veröffentlicht in:	Journal of interferon & cytokine research 2000-02, Vol.20 (2), p.225-233
Hauptverfasser:	Flint, A P, Abayasekara, D R, Wheeler-Jones, C P, Riley, P R, Kaluz, S, Kaluzova, M, Sheldrick, E L, Fisher, P A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Cell Line Chloramphenicol O-Acetyltransferase - genetics Enzyme Activation - drug effects Enzyme Inhibitors - pharmacology Estradiol - metabolism Gene Expression - drug effects Genes, Reporter Indoles - pharmacology Interferon Type I - pharmacology Kinetics Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases - metabolism Phosphorylation Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Receptors, Estrogen - drug effects Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Recombinant Proteins
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