Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat
Single-unit activity was monitored in the interpositus nucleus of the cerebellum during standard delay conditioning of the eyeblink response in freely-moving rats. The rats were implanted with recording electrodes in the interpositus nucleus then received paired presentations of a tone-conditioned s...
Gespeichert in:
| Veröffentlicht in: | Brain research 2001-06, Vol.905 (1), p.171-177 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 177 |
|---|---|
| container_issue | 1 |
| container_start_page | 171 |
| container_title | Brain research |
| container_volume | 905 |
| creator | Rogers, Ronald F Britton, Gabrielle B Steinmetz, Joseph E |
| description | Single-unit activity was monitored in the interpositus nucleus of the cerebellum during standard delay conditioning of the eyeblink response in freely-moving rats. The rats were implanted with recording electrodes in the interpositus nucleus then received paired presentations of a tone-conditioned stimulus (CS) and eye-shock unconditioned stimulus during acquisition training. The acquisition training was followed by CS-alone extinction training. Learning-related activity in the interpositus nucleus developed over the course of acquisition training and then activity returned to baseline levels during subsequent extinction training. These findings are consistent with rabbit studies that have demonstrated similar changes in neuronal activity in the interpositus nucleus over the course of acquisition and extinction of the eyeblink response, thus providing strong evidence for the generality of the neural substrates of eyeblink conditioning across species. |
| doi_str_mv | 10.1016/S0006-8993(01)02532-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70965766</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S000689930102532X</els_id><sourcerecordid>70965766</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-8daa35e940a04fb4b6636cf72f5fcf037a1371c73dfce8b5cb0c91123c779b413</originalsourceid><addsrcrecordid>eNqFkUtv1DAUha0KRKeFn9AqGypYBK4fieNVVVUUkEZiUZC6sxz7GlwyyWA7I82_r-chuuzKtvydc6_OIeSCwicKtP18DwBt3SnFPwD9CKzhrH44IQvaSVa3TMArsviPnJKzlB7Lk3MFb8gppYJxUGxB5iWaOIbxdx1xMBldFcaMcT2lkOdUGZvDJuRtFVJlpzFh3BTE2DilVKU12oAFKtc8u1B-3ByLV4Vb7Icw_t1pXMhh2k0ozlX-g1U0-S157c2Q8N3xPCe_7r78vP1WL398_X57s6xtIyDXnTOGN6gEGBC-F33b8tZ6yXzjrQcuDeWSWsmdt9j1je3BKkoZt1KqXlB-Tq4Ovus4_ZsxZb0KyeIwmBGnOWkJqm1kcX0JpB1IxTtRwOYA7iOI6PU6hpWJW01B74rR-2L0LnUNVO-L0Q9Fd3kcMPcrdM-qYxMFeH8ETLJm8NGMNqRnTkAHjDaFuz5wWHLbBIw6lRJGiy5EtFm7KbywyhPh7Kzy</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>18079384</pqid></control><display><type>article</type><title>Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Rogers, Ronald F ; Britton, Gabrielle B ; Steinmetz, Joseph E</creator><creatorcontrib>Rogers, Ronald F ; Britton, Gabrielle B ; Steinmetz, Joseph E</creatorcontrib><description>Single-unit activity was monitored in the interpositus nucleus of the cerebellum during standard delay conditioning of the eyeblink response in freely-moving rats. The rats were implanted with recording electrodes in the interpositus nucleus then received paired presentations of a tone-conditioned stimulus (CS) and eye-shock unconditioned stimulus during acquisition training. The acquisition training was followed by CS-alone extinction training. Learning-related activity in the interpositus nucleus developed over the course of acquisition training and then activity returned to baseline levels during subsequent extinction training. These findings are consistent with rabbit studies that have demonstrated similar changes in neuronal activity in the interpositus nucleus over the course of acquisition and extinction of the eyeblink response, thus providing strong evidence for the generality of the neural substrates of eyeblink conditioning across species.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/S0006-8993(01)02532-X</identifier><identifier>PMID: 11423092</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Action Potentials - physiology ; Anatomical correlates of behavior ; Animals ; Behavior, Animal - physiology ; Behavioral psychophysiology ; Biological and medical sciences ; Cerebellar Nuclei - cytology ; Cerebellar Nuclei - physiology ; Cerebellum ; Classical conditioning ; Conditioning, Eyelid - physiology ; Eyelid ; Fundamental and applied biological sciences. Psychology ; Interpositus nucleus ; Learning - physiology ; Microelectrodes ; Neurons - cytology ; Neurons - physiology ; Psychology. Psychoanalysis. Psychiatry ; Psychology. Psychophysiology ; Rabbits ; Rat ; Rats ; Rats, Sprague-Dawley</subject><ispartof>Brain research, 2001-06, Vol.905 (1), p.171-177</ispartof><rights>2001</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-8daa35e940a04fb4b6636cf72f5fcf037a1371c73dfce8b5cb0c91123c779b413</citedby><cites>FETCH-LOGICAL-c540t-8daa35e940a04fb4b6636cf72f5fcf037a1371c73dfce8b5cb0c91123c779b413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0006-8993(01)02532-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14080215$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11423092$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rogers, Ronald F</creatorcontrib><creatorcontrib>Britton, Gabrielle B</creatorcontrib><creatorcontrib>Steinmetz, Joseph E</creatorcontrib><title>Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Single-unit activity was monitored in the interpositus nucleus of the cerebellum during standard delay conditioning of the eyeblink response in freely-moving rats. The rats were implanted with recording electrodes in the interpositus nucleus then received paired presentations of a tone-conditioned stimulus (CS) and eye-shock unconditioned stimulus during acquisition training. The acquisition training was followed by CS-alone extinction training. Learning-related activity in the interpositus nucleus developed over the course of acquisition training and then activity returned to baseline levels during subsequent extinction training. These findings are consistent with rabbit studies that have demonstrated similar changes in neuronal activity in the interpositus nucleus over the course of acquisition and extinction of the eyeblink response, thus providing strong evidence for the generality of the neural substrates of eyeblink conditioning across species.</description><subject>Action Potentials - physiology</subject><subject>Anatomical correlates of behavior</subject><subject>Animals</subject><subject>Behavior, Animal - physiology</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Cerebellar Nuclei - cytology</subject><subject>Cerebellar Nuclei - physiology</subject><subject>Cerebellum</subject><subject>Classical conditioning</subject><subject>Conditioning, Eyelid - physiology</subject><subject>Eyelid</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Interpositus nucleus</subject><subject>Learning - physiology</subject><subject>Microelectrodes</subject><subject>Neurons - cytology</subject><subject>Neurons - physiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Rabbits</subject><subject>Rat</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtv1DAUha0KRKeFn9AqGypYBK4fieNVVVUUkEZiUZC6sxz7GlwyyWA7I82_r-chuuzKtvydc6_OIeSCwicKtP18DwBt3SnFPwD9CKzhrH44IQvaSVa3TMArsviPnJKzlB7Lk3MFb8gppYJxUGxB5iWaOIbxdx1xMBldFcaMcT2lkOdUGZvDJuRtFVJlpzFh3BTE2DilVKU12oAFKtc8u1B-3ByLV4Vb7Icw_t1pXMhh2k0ozlX-g1U0-S157c2Q8N3xPCe_7r78vP1WL398_X57s6xtIyDXnTOGN6gEGBC-F33b8tZ6yXzjrQcuDeWSWsmdt9j1je3BKkoZt1KqXlB-Tq4Ovus4_ZsxZb0KyeIwmBGnOWkJqm1kcX0JpB1IxTtRwOYA7iOI6PU6hpWJW01B74rR-2L0LnUNVO-L0Q9Fd3kcMPcrdM-qYxMFeH8ETLJm8NGMNqRnTkAHjDaFuz5wWHLbBIw6lRJGiy5EtFm7KbywyhPh7Kzy</recordid><startdate>20010629</startdate><enddate>20010629</enddate><creator>Rogers, Ronald F</creator><creator>Britton, Gabrielle B</creator><creator>Steinmetz, Joseph E</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20010629</creationdate><title>Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat</title><author>Rogers, Ronald F ; Britton, Gabrielle B ; Steinmetz, Joseph E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-8daa35e940a04fb4b6636cf72f5fcf037a1371c73dfce8b5cb0c91123c779b413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Action Potentials - physiology</topic><topic>Anatomical correlates of behavior</topic><topic>Animals</topic><topic>Behavior, Animal - physiology</topic><topic>Behavioral psychophysiology</topic><topic>Biological and medical sciences</topic><topic>Cerebellar Nuclei - cytology</topic><topic>Cerebellar Nuclei - physiology</topic><topic>Cerebellum</topic><topic>Classical conditioning</topic><topic>Conditioning, Eyelid - physiology</topic><topic>Eyelid</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Interpositus nucleus</topic><topic>Learning - physiology</topic><topic>Microelectrodes</topic><topic>Neurons - cytology</topic><topic>Neurons - physiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Rabbits</topic><topic>Rat</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rogers, Ronald F</creatorcontrib><creatorcontrib>Britton, Gabrielle B</creatorcontrib><creatorcontrib>Steinmetz, Joseph E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rogers, Ronald F</au><au>Britton, Gabrielle B</au><au>Steinmetz, Joseph E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>2001-06-29</date><risdate>2001</risdate><volume>905</volume><issue>1</issue><spage>171</spage><epage>177</epage><pages>171-177</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>Single-unit activity was monitored in the interpositus nucleus of the cerebellum during standard delay conditioning of the eyeblink response in freely-moving rats. The rats were implanted with recording electrodes in the interpositus nucleus then received paired presentations of a tone-conditioned stimulus (CS) and eye-shock unconditioned stimulus during acquisition training. The acquisition training was followed by CS-alone extinction training. Learning-related activity in the interpositus nucleus developed over the course of acquisition training and then activity returned to baseline levels during subsequent extinction training. These findings are consistent with rabbit studies that have demonstrated similar changes in neuronal activity in the interpositus nucleus over the course of acquisition and extinction of the eyeblink response, thus providing strong evidence for the generality of the neural substrates of eyeblink conditioning across species.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>11423092</pmid><doi>10.1016/S0006-8993(01)02532-X</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 2001-06, Vol.905 (1), p.171-177 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70965766 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Action Potentials - physiology Anatomical correlates of behavior Animals Behavior, Animal - physiology Behavioral psychophysiology Biological and medical sciences Cerebellar Nuclei - cytology Cerebellar Nuclei - physiology Cerebellum Classical conditioning Conditioning, Eyelid - physiology Eyelid Fundamental and applied biological sciences. Psychology Interpositus nucleus Learning - physiology Microelectrodes Neurons - cytology Neurons - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rabbits Rat Rats Rats, Sprague-Dawley |
| title | Learning-related interpositus activity is conserved across species as studied during eyeblink conditioning in the rat |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T17%3A24%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Learning-related%20interpositus%20activity%20is%20conserved%20across%20species%20as%20studied%20during%20eyeblink%20conditioning%20in%20the%20rat&rft.jtitle=Brain%20research&rft.au=Rogers,%20Ronald%20F&rft.date=2001-06-29&rft.volume=905&rft.issue=1&rft.spage=171&rft.epage=177&rft.pages=171-177&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/S0006-8993(01)02532-X&rft_dat=%3Cproquest_cross%3E70965766%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=18079384&rft_id=info:pmid/11423092&rft_els_id=S000689930102532X&rfr_iscdi=true |