Synthetic bone graft substitutes

Replacement of extensive local bone loss is a significant clinical challenge. There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone gr...

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Veröffentlicht in:ANZ journal of surgery 2001-06, Vol.71 (6), p.354-361
Hauptverfasser: Moore, William R., Graves, Stephen E., Bain, Gregory I.
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container_title ANZ journal of surgery
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creator Moore, William R.
Graves, Stephen E.
Bain, Gregory I.
description Replacement of extensive local bone loss is a significant clinical challenge. There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone graft and limitations in the quantity of bone available. Alternatively allografts have been reported to have a significant incidence of postoperative infection and fracture as well as the potential risk of disease transmission. During the past 30 years a variety of synthetic bone graft substitutes has been developed with the aim to minimize these complications. The benefits of synthetic grafts include availability, sterility and reduced morbidity. The present article examines the relevance of synthetic bone graft substitutes, their mechanical properties and clinical application.
doi_str_mv 10.1046/j.1440-1622.2001.02128.x
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects allograft
Aluminum Oxide - therapeutic use
autograft
Biocompatible Materials - therapeutic use
Bone Cements
bone graft substitute
Bone Regeneration
Bone Substitutes - therapeutic use
Bone Transplantation - methods
Calcium Phosphates - therapeutic use
Calcium Sulfate - therapeutic use
Durapatite - therapeutic use
future
Humans
Hydroxyapatites - therapeutic use
title Synthetic bone graft substitutes
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