Synthetic bone graft substitutes
Replacement of extensive local bone loss is a significant clinical challenge. There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone gr...
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Veröffentlicht in: | ANZ journal of surgery 2001-06, Vol.71 (6), p.354-361 |
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container_title | ANZ journal of surgery |
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creator | Moore, William R. Graves, Stephen E. Bain, Gregory I. |
description | Replacement of extensive local bone loss is a significant clinical challenge. There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone graft and limitations in the quantity of bone available. Alternatively allografts have been reported to have a significant incidence of postoperative infection and fracture as well as the potential risk of disease transmission. During the past 30 years a variety of synthetic bone graft substitutes has been developed with the aim to minimize these complications. The benefits of synthetic grafts include availability, sterility and reduced morbidity. The present article examines the relevance of synthetic bone graft substitutes, their mechanical properties and clinical application. |
doi_str_mv | 10.1046/j.1440-1622.2001.02128.x |
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There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone graft and limitations in the quantity of bone available. Alternatively allografts have been reported to have a significant incidence of postoperative infection and fracture as well as the potential risk of disease transmission. During the past 30 years a variety of synthetic bone graft substitutes has been developed with the aim to minimize these complications. The benefits of synthetic grafts include availability, sterility and reduced morbidity. The present article examines the relevance of synthetic bone graft substitutes, their mechanical properties and clinical application.</description><subject>allograft</subject><subject>Aluminum Oxide - therapeutic use</subject><subject>autograft</subject><subject>Biocompatible Materials - therapeutic use</subject><subject>Bone Cements</subject><subject>bone graft substitute</subject><subject>Bone Regeneration</subject><subject>Bone Substitutes - therapeutic use</subject><subject>Bone Transplantation - methods</subject><subject>Calcium Phosphates - therapeutic use</subject><subject>Calcium Sulfate - therapeutic use</subject><subject>Durapatite - therapeutic use</subject><subject>future</subject><subject>Humans</subject><subject>Hydroxyapatites - therapeutic use</subject><issn>1445-1433</issn><issn>1445-2197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkM9LwzAUgIMobk7_BenJW2tekibNwcMYbipjIvMHeAlt-qqd3TqbFrf_3tYNvXrKg3zfe_AR4gENgAp5uQhACOqDZCxglEJAGbAo2ByQfvsR-gy0OtzPIDjvkRPnFi0opQ6PSQ9AUN06feLNt6v6Hevcekm5Qu-tirPac03i6rxuanSn5CiLC4dn-3dAnsbXj6Mbf3o_uR0Np74VUkc-pFRbK1JGlUKGMSJkMUolIYrCBGiMOrEyxYTLLGVKS8otVxkTqQWW6JAPyMVu77oqPxt0tVnmzmJRxCssG2cU1TKESLdgtANtVTpXYWbWVb6Mq60Baro6ZmG6OqarY7o65qeO2bTq-f5Gkywx_RP3OVrgagd85QVu_73YDGfzbmp9f-fnrsbNrx9XH0YqrkLzMpuYh0jcvfKxMs_8Gy9BgRU</recordid><startdate>200106</startdate><enddate>200106</enddate><creator>Moore, William R.</creator><creator>Graves, Stephen E.</creator><creator>Bain, Gregory I.</creator><general>Blackwell Science Pty</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200106</creationdate><title>Synthetic bone graft substitutes</title><author>Moore, William R. ; Graves, Stephen E. ; Bain, Gregory I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4698-1d09cc4d2077e2eaee1fae6761885b10ae9bc6deb36fd279603c37f24dc12b953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>allograft</topic><topic>Aluminum Oxide - therapeutic use</topic><topic>autograft</topic><topic>Biocompatible Materials - therapeutic use</topic><topic>Bone Cements</topic><topic>bone graft substitute</topic><topic>Bone Regeneration</topic><topic>Bone Substitutes - therapeutic use</topic><topic>Bone Transplantation - methods</topic><topic>Calcium Phosphates - therapeutic use</topic><topic>Calcium Sulfate - therapeutic use</topic><topic>Durapatite - therapeutic use</topic><topic>future</topic><topic>Humans</topic><topic>Hydroxyapatites - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moore, William R.</creatorcontrib><creatorcontrib>Graves, Stephen E.</creatorcontrib><creatorcontrib>Bain, Gregory I.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ANZ journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moore, William R.</au><au>Graves, Stephen E.</au><au>Bain, Gregory I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthetic bone graft substitutes</atitle><jtitle>ANZ journal of surgery</jtitle><addtitle>ANZ Journal of Surgery</addtitle><date>2001-06</date><risdate>2001</risdate><volume>71</volume><issue>6</issue><spage>354</spage><epage>361</epage><pages>354-361</pages><issn>1445-1433</issn><eissn>1445-2197</eissn><abstract>Replacement of extensive local bone loss is a significant clinical challenge. There are a variety of techniques available to the surgeon to manage this problem, each with their own advantages and disadvantages. It is well known that there is morbidity associated with harvesting of autogenous bone graft and limitations in the quantity of bone available. Alternatively allografts have been reported to have a significant incidence of postoperative infection and fracture as well as the potential risk of disease transmission. During the past 30 years a variety of synthetic bone graft substitutes has been developed with the aim to minimize these complications. The benefits of synthetic grafts include availability, sterility and reduced morbidity. The present article examines the relevance of synthetic bone graft substitutes, their mechanical properties and clinical application.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>11409021</pmid><doi>10.1046/j.1440-1622.2001.02128.x</doi><tpages>8</tpages></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | allograft Aluminum Oxide - therapeutic use autograft Biocompatible Materials - therapeutic use Bone Cements bone graft substitute Bone Regeneration Bone Substitutes - therapeutic use Bone Transplantation - methods Calcium Phosphates - therapeutic use Calcium Sulfate - therapeutic use Durapatite - therapeutic use future Humans Hydroxyapatites - therapeutic use |
title | Synthetic bone graft substitutes |
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