Relation of Prefrontal Cortex Dysfunction to Working Memory and Symptoms in Schizophrenia

OBJECTIVE: The dorsolateral prefrontal cortex has been implicated in both working memory and the pathophysiology of schizophrenia. A relationship among dorsolateral prefrontal cortex activity, working memory dysfunction, and symptoms in schizophrenia has not been firmly established, partly because o...

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Veröffentlicht in:	The American journal of psychiatry 2001-07, Vol.158 (7), p.1105-1113
Hauptverfasser:	Perlstein, William M., Carter, Cameron S., Noll, Douglas C., Cohen, Jonathan D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Biological and medical sciences Brain Cognition & reasoning Functional Laterality - physiology Humans Magnetic Resonance Imaging Medical sciences Memory Memory Disorders - diagnosis Memory Disorders - physiopathology Neuropsychological Tests - statistics & numerical data Prefrontal Cortex - physiopathology Prefrontal cortex dysfunction Psychiatric Status Rating Scales - statistics & numerical data Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - physiology Psychopathology. Psychiatry Psychoses Reaction Time - physiology Schizophrenia Schizophrenia - diagnosis Schizophrenia - physiopathology Schizophrenic Psychology Task Performance and Analysis Working memory
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