A Novel Member of the BTB/POZ Family, PATZ, Associates with the RNF4 RING Finger Protein and Acts as a Transcriptional Repressor

We have identified a novel human gene encoding a 59-kDa POZ-AT hook-zinc finger protein (PATZ) that interacts with RNF4, a mediator of androgen receptor activity, and acts as a transcriptional repressor. PATZ cDNA was isolated through a two-hybrid interaction screening using the RING finger protein...

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Veröffentlicht in:	The Journal of biological chemistry 2000-03, Vol.275 (11), p.7894-7901
Hauptverfasser:	Fedele, Monica, Benvenuto, Giovanna, Pero, Raffaela, Majello, Barbara, Battista, Sabrina, Lembo, Francesca, Vollono, Erminia, Day, Patricia M., Santoro, Massimo, Lania, Luigi, Bruni, Carmelo Bruno, Fusco, Alfredo, Chiariotti, Lorenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals DNA-Binding Proteins - metabolism High Mobility Group Proteins - metabolism HMGA1a Protein Humans Kruppel-Like Transcription Factors Mice Molecular Sequence Data Neoplasm Proteins Nuclear Proteins PATZ protein Protein Binding Repressor Proteins - classification Repressor Proteins - genetics Repressor Proteins - metabolism RING finger proteins RNF4 protein Sequence Homology, Amino Acid Transcription Factors - metabolism Transcription, Genetic Two-Hybrid System Techniques Ubiquitin-Protein Ligases Zinc Fingers
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