Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer
Background and Aims : The relationship between peptic ulcer, autonomic activity and the incidence of Helicobacter pylori infection in untreated hypertensive patients complicated with peptic ulcer were evaluated. Methods : Ten hypertensive patients with peptic ulcer (HT‐PU group), 15 untreated essent...
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| Veröffentlicht in: | Journal of gastroenterology and hepatology 2000-01, Vol.15 (1), p.40-44 |
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| creator | Yukinaka, Michiko Nomura, Masahiro Saijyo, Tetsuya Nada, Tomomi Miyajima, Hitoshi Kondo, Yuki Saito, Ken Nakaya, Yutaka Ito, Susumu |
| description | Background and Aims
: The relationship between peptic ulcer, autonomic activity and the incidence of Helicobacter pylori infection in untreated hypertensive patients complicated with peptic ulcer were evaluated.
Methods
: Ten hypertensive patients with peptic ulcer (HT‐PU group), 15 untreated essential hypertensive patients without peptic ulcer (HT group) and 10 normal subjects (N group) were enrolled, and a power spectral analysis was performed in each subject. A biopsy urease test was used to detect infection by H. pylori.
Results
: No significant differences were observed in the values of mean low‐frequency (LF) power between the three groups. However, the mean high‐frequency (HF) power in the HT‐PU group was significantly greater than those of the HT and N groups (P < 0.01). The mean LF/HF ratios in the HT‐PU and HT groups were significantly greater than that of the N group (P < 0.01). With respect to H. pylori infection, no significant differences between the three groups were observed. Sympathetic activity (LF power) was increased in the HT and HT‐PU groups. Furthermore, parasympathetic activity (HF power) was increased in the HT‐PU group.
Conclusions
: These findings suggest the participation of increased parasympathetic activity in peptic ulcer patients. Therefore, it is suggested that new techniques, such as spectral analysis of heart rate variability, as used in this study, will clarify the relationship between peptic ulcer and autonomic nervous function. |
| doi_str_mv | 10.1046/j.1440-1746.2000.02052.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70960707</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70960707</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4322-e2f17664a3e84e1f2f919f00a00a59bac79635b31fad7a615e5f8bc3a1a2bfa73</originalsourceid><addsrcrecordid>eNqNkMFu1DAQhi0EokvhFVAOiFuCHSdxfOCAqu4upSpSBerRmnjHqpfECXbS7r49TrMqHJEs2aP5_hn5IyRhNGO0qD7tM1YUNGWiqLKcUprRnJZ5dnhBVs-Nl2RFa1amkjN5Rt6EsI9gQUX5mpwxKpiMzIq4ywdoJxht75LeJDCNves7qxOH_qGfQmImp5-61iVD5NCNIXm0432CIcTCQpvcHwf0I7owc7rvhtZqGHG3cAMOYxw4tRr9W_LKQBvw3ek-Jz_Xlz8utun1983Xiy_XqS54nqeYGyaqqgCOdYHM5EYyaSiFeErZgBay4mXDmYGdgIqVWJq60RwY5I0Bwc_Jx2Xu4PvfE4ZRdTZobFtwGH-lBJUVFXQG6wXUvg_Bo1GDtx34o2JUza7VXs1K1axUza7Vk2t1iNH3px1T0-Hun-AiNwIfTgAEDa3x4LQNfzley0LO2OcFe7QtHv97v7rabOdXzKdL3oYRD8958L9UJbgo1d3NRt1uv13d3K3X6pb_ATcIrCg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70960707</pqid></control><display><type>article</type><title>Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer</title><source>Wiley Online Library - AutoHoldings Journals</source><source>MEDLINE</source><creator>Yukinaka, Michiko ; Nomura, Masahiro ; Saijyo, Tetsuya ; Nada, Tomomi ; Miyajima, Hitoshi ; Kondo, Yuki ; Saito, Ken ; Nakaya, Yutaka ; Ito, Susumu</creator><creatorcontrib>Yukinaka, Michiko ; Nomura, Masahiro ; Saijyo, Tetsuya ; Nada, Tomomi ; Miyajima, Hitoshi ; Kondo, Yuki ; Saito, Ken ; Nakaya, Yutaka ; Ito, Susumu</creatorcontrib><description>Background and Aims
: The relationship between peptic ulcer, autonomic activity and the incidence of Helicobacter pylori infection in untreated hypertensive patients complicated with peptic ulcer were evaluated.
Methods
: Ten hypertensive patients with peptic ulcer (HT‐PU group), 15 untreated essential hypertensive patients without peptic ulcer (HT group) and 10 normal subjects (N group) were enrolled, and a power spectral analysis was performed in each subject. A biopsy urease test was used to detect infection by H. pylori.
Results
: No significant differences were observed in the values of mean low‐frequency (LF) power between the three groups. However, the mean high‐frequency (HF) power in the HT‐PU group was significantly greater than those of the HT and N groups (P < 0.01). The mean LF/HF ratios in the HT‐PU and HT groups were significantly greater than that of the N group (P < 0.01). With respect to H. pylori infection, no significant differences between the three groups were observed. Sympathetic activity (LF power) was increased in the HT and HT‐PU groups. Furthermore, parasympathetic activity (HF power) was increased in the HT‐PU group.
Conclusions
: These findings suggest the participation of increased parasympathetic activity in peptic ulcer patients. Therefore, it is suggested that new techniques, such as spectral analysis of heart rate variability, as used in this study, will clarify the relationship between peptic ulcer and autonomic nervous function.</description><identifier>ISSN: 0815-9319</identifier><identifier>EISSN: 1440-1746</identifier><identifier>DOI: 10.1046/j.1440-1746.2000.02052.x</identifier><identifier>PMID: 10719746</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Science Pty</publisher><subject>Arterial hypertension. Arterial hypotension ; autonomic nervous function ; Autonomic Nervous System - physiopathology ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Circadian Rhythm ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Electrocardiography, Ambulatory - methods ; essential hypertension ; Female ; Heart Rate - physiology ; heart rate variability ; Helicobacter Infections - complications ; Helicobacter Infections - microbiology ; Helicobacter Infections - physiopathology ; Helicobacter pylori - isolation & purification ; Humans ; Hypertension - complications ; Hypertension - physiopathology ; Male ; Medical sciences ; Middle Aged ; peptic ulcer ; Peptic Ulcer - complications ; Peptic Ulcer - microbiology ; Peptic Ulcer - physiopathology ; Reference Values ; Signal Processing, Computer-Assisted</subject><ispartof>Journal of gastroenterology and hepatology, 2000-01, Vol.15 (1), p.40-44</ispartof><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4322-e2f17664a3e84e1f2f919f00a00a59bac79635b31fad7a615e5f8bc3a1a2bfa73</citedby><cites>FETCH-LOGICAL-c4322-e2f17664a3e84e1f2f919f00a00a59bac79635b31fad7a615e5f8bc3a1a2bfa73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1440-1746.2000.02052.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1440-1746.2000.02052.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,1411,4036,4037,23909,23910,25118,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1389496$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10719746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yukinaka, Michiko</creatorcontrib><creatorcontrib>Nomura, Masahiro</creatorcontrib><creatorcontrib>Saijyo, Tetsuya</creatorcontrib><creatorcontrib>Nada, Tomomi</creatorcontrib><creatorcontrib>Miyajima, Hitoshi</creatorcontrib><creatorcontrib>Kondo, Yuki</creatorcontrib><creatorcontrib>Saito, Ken</creatorcontrib><creatorcontrib>Nakaya, Yutaka</creatorcontrib><creatorcontrib>Ito, Susumu</creatorcontrib><title>Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer</title><title>Journal of gastroenterology and hepatology</title><addtitle>J Gastroenterol Hepatol</addtitle><description>Background and Aims
: The relationship between peptic ulcer, autonomic activity and the incidence of Helicobacter pylori infection in untreated hypertensive patients complicated with peptic ulcer were evaluated.
Methods
: Ten hypertensive patients with peptic ulcer (HT‐PU group), 15 untreated essential hypertensive patients without peptic ulcer (HT group) and 10 normal subjects (N group) were enrolled, and a power spectral analysis was performed in each subject. A biopsy urease test was used to detect infection by H. pylori.
Results
: No significant differences were observed in the values of mean low‐frequency (LF) power between the three groups. However, the mean high‐frequency (HF) power in the HT‐PU group was significantly greater than those of the HT and N groups (P < 0.01). The mean LF/HF ratios in the HT‐PU and HT groups were significantly greater than that of the N group (P < 0.01). With respect to H. pylori infection, no significant differences between the three groups were observed. Sympathetic activity (LF power) was increased in the HT and HT‐PU groups. Furthermore, parasympathetic activity (HF power) was increased in the HT‐PU group.
Conclusions
: These findings suggest the participation of increased parasympathetic activity in peptic ulcer patients. Therefore, it is suggested that new techniques, such as spectral analysis of heart rate variability, as used in this study, will clarify the relationship between peptic ulcer and autonomic nervous function.</description><subject>Arterial hypertension. Arterial hypotension</subject><subject>autonomic nervous function</subject><subject>Autonomic Nervous System - physiopathology</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Circadian Rhythm</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Electrocardiography, Ambulatory - methods</subject><subject>essential hypertension</subject><subject>Female</subject><subject>Heart Rate - physiology</subject><subject>heart rate variability</subject><subject>Helicobacter Infections - complications</subject><subject>Helicobacter Infections - microbiology</subject><subject>Helicobacter Infections - physiopathology</subject><subject>Helicobacter pylori - isolation & purification</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Hypertension - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>peptic ulcer</subject><subject>Peptic Ulcer - complications</subject><subject>Peptic Ulcer - microbiology</subject><subject>Peptic Ulcer - physiopathology</subject><subject>Reference Values</subject><subject>Signal Processing, Computer-Assisted</subject><issn>0815-9319</issn><issn>1440-1746</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFu1DAQhi0EokvhFVAOiFuCHSdxfOCAqu4upSpSBerRmnjHqpfECXbS7r49TrMqHJEs2aP5_hn5IyRhNGO0qD7tM1YUNGWiqLKcUprRnJZ5dnhBVs-Nl2RFa1amkjN5Rt6EsI9gQUX5mpwxKpiMzIq4ywdoJxht75LeJDCNves7qxOH_qGfQmImp5-61iVD5NCNIXm0432CIcTCQpvcHwf0I7owc7rvhtZqGHG3cAMOYxw4tRr9W_LKQBvw3ek-Jz_Xlz8utun1983Xiy_XqS54nqeYGyaqqgCOdYHM5EYyaSiFeErZgBay4mXDmYGdgIqVWJq60RwY5I0Bwc_Jx2Xu4PvfE4ZRdTZobFtwGH-lBJUVFXQG6wXUvg_Bo1GDtx34o2JUza7VXs1K1axUza7Vk2t1iNH3px1T0-Hun-AiNwIfTgAEDa3x4LQNfzley0LO2OcFe7QtHv97v7rabOdXzKdL3oYRD8958L9UJbgo1d3NRt1uv13d3K3X6pb_ATcIrCg</recordid><startdate>200001</startdate><enddate>200001</enddate><creator>Yukinaka, Michiko</creator><creator>Nomura, Masahiro</creator><creator>Saijyo, Tetsuya</creator><creator>Nada, Tomomi</creator><creator>Miyajima, Hitoshi</creator><creator>Kondo, Yuki</creator><creator>Saito, Ken</creator><creator>Nakaya, Yutaka</creator><creator>Ito, Susumu</creator><general>Blackwell Science Pty</general><general>Blackwell Science</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200001</creationdate><title>Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer</title><author>Yukinaka, Michiko ; Nomura, Masahiro ; Saijyo, Tetsuya ; Nada, Tomomi ; Miyajima, Hitoshi ; Kondo, Yuki ; Saito, Ken ; Nakaya, Yutaka ; Ito, Susumu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4322-e2f17664a3e84e1f2f919f00a00a59bac79635b31fad7a615e5f8bc3a1a2bfa73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Arterial hypertension. Arterial hypotension</topic><topic>autonomic nervous function</topic><topic>Autonomic Nervous System - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Circadian Rhythm</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Electrocardiography, Ambulatory - methods</topic><topic>essential hypertension</topic><topic>Female</topic><topic>Heart Rate - physiology</topic><topic>heart rate variability</topic><topic>Helicobacter Infections - complications</topic><topic>Helicobacter Infections - microbiology</topic><topic>Helicobacter Infections - physiopathology</topic><topic>Helicobacter pylori - isolation & purification</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Hypertension - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>peptic ulcer</topic><topic>Peptic Ulcer - complications</topic><topic>Peptic Ulcer - microbiology</topic><topic>Peptic Ulcer - physiopathology</topic><topic>Reference Values</topic><topic>Signal Processing, Computer-Assisted</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yukinaka, Michiko</creatorcontrib><creatorcontrib>Nomura, Masahiro</creatorcontrib><creatorcontrib>Saijyo, Tetsuya</creatorcontrib><creatorcontrib>Nada, Tomomi</creatorcontrib><creatorcontrib>Miyajima, Hitoshi</creatorcontrib><creatorcontrib>Kondo, Yuki</creatorcontrib><creatorcontrib>Saito, Ken</creatorcontrib><creatorcontrib>Nakaya, Yutaka</creatorcontrib><creatorcontrib>Ito, Susumu</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastroenterology and hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yukinaka, Michiko</au><au>Nomura, Masahiro</au><au>Saijyo, Tetsuya</au><au>Nada, Tomomi</au><au>Miyajima, Hitoshi</au><au>Kondo, Yuki</au><au>Saito, Ken</au><au>Nakaya, Yutaka</au><au>Ito, Susumu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer</atitle><jtitle>Journal of gastroenterology and hepatology</jtitle><addtitle>J Gastroenterol Hepatol</addtitle><date>2000-01</date><risdate>2000</risdate><volume>15</volume><issue>1</issue><spage>40</spage><epage>44</epage><pages>40-44</pages><issn>0815-9319</issn><eissn>1440-1746</eissn><abstract>Background and Aims
: The relationship between peptic ulcer, autonomic activity and the incidence of Helicobacter pylori infection in untreated hypertensive patients complicated with peptic ulcer were evaluated.
Methods
: Ten hypertensive patients with peptic ulcer (HT‐PU group), 15 untreated essential hypertensive patients without peptic ulcer (HT group) and 10 normal subjects (N group) were enrolled, and a power spectral analysis was performed in each subject. A biopsy urease test was used to detect infection by H. pylori.
Results
: No significant differences were observed in the values of mean low‐frequency (LF) power between the three groups. However, the mean high‐frequency (HF) power in the HT‐PU group was significantly greater than those of the HT and N groups (P < 0.01). The mean LF/HF ratios in the HT‐PU and HT groups were significantly greater than that of the N group (P < 0.01). With respect to H. pylori infection, no significant differences between the three groups were observed. Sympathetic activity (LF power) was increased in the HT and HT‐PU groups. Furthermore, parasympathetic activity (HF power) was increased in the HT‐PU group.
Conclusions
: These findings suggest the participation of increased parasympathetic activity in peptic ulcer patients. Therefore, it is suggested that new techniques, such as spectral analysis of heart rate variability, as used in this study, will clarify the relationship between peptic ulcer and autonomic nervous function.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>10719746</pmid><doi>10.1046/j.1440-1746.2000.02052.x</doi><tpages>5</tpages></addata></record> |
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| subjects | Arterial hypertension. Arterial hypotension autonomic nervous function Autonomic Nervous System - physiopathology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Circadian Rhythm Clinical manifestations. Epidemiology. Investigative techniques. Etiology Electrocardiography, Ambulatory - methods essential hypertension Female Heart Rate - physiology heart rate variability Helicobacter Infections - complications Helicobacter Infections - microbiology Helicobacter Infections - physiopathology Helicobacter pylori - isolation & purification Humans Hypertension - complications Hypertension - physiopathology Male Medical sciences Middle Aged peptic ulcer Peptic Ulcer - complications Peptic Ulcer - microbiology Peptic Ulcer - physiopathology Reference Values Signal Processing, Computer-Assisted |
| title | Evaluation of autonomic nervous function in patients with essential hypertension complicated with peptic ulcer |
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