Antifungal activity of itraconazole compared with hydroxy-itraconazole in vitro

Microbroth dilution tests in vitro showed the same IC(50) values for itraconazole and hydroxy-itraconazole, within a mode +/- one dilution range of experimental error, for 90% of 1481 isolates of pathogenic fungi, representing 48 genera. Some 10-15% of Candida glabrata and Trichophyton mentagrophyte...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2000-03, Vol.45 (3), p.371-373
Hauptverfasser:	ODDS, F. C, BOSSCHE, H. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - pharmacology Biological and medical sciences Candida - drug effects Candida albicans Candida glabrata Candida kefyr Fungi - drug effects hydroxyitraconazole itraconazole Itraconazole - analogs & derivatives Itraconazole - pharmacology Medical sciences Microbial Sensitivity Tests Pharmacology. Drug treatments Trichophyton - drug effects Trichophyton mentagrophytes
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