Estradiol Enhances the Induction of Homosynaptic Long-Term Depression in the CA1 Region of the Adult, Ovariectomized Rat

An ovarian steroid-dependent cycle of synaptogenesis and synapse shedding occurs naturally in the hippocampus of the adult female rat. The newly formed axospinous synapses in CA1 may differ functionally from extant axospinous synapses, e.g., in terms of their modifiability. Here we assess whether es...

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Veröffentlicht in:	Neurobiology of learning and memory 2000-03, Vol.73 (2), p.180-187
Hauptverfasser:	Desmond, Nancy L, Zhang, De Xing, Levy, William B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavioral psychophysiology Biological and medical sciences CA1 Depression, Chemical Electrophysiology estradiol Estradiol - metabolism Estradiol - physiology Estrus - physiology Female Fundamental and applied biological sciences. Psychology hippocampal slice hippocampus Hippocampus - metabolism Hippocampus - physiology Hippocampus - ultrastructure In Vitro Techniques long-term depression long-term potentiation Neuronal Plasticity - physiology Neurons - physiology Ovariectomy plasticity Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Synaptic Transmission - physiology
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