A Role for Bovine Herpesvirus 1 (BHV-1) Glycoprotein E (gE) Tyrosine Phosphorylation in Replication of BHV-1 Wild-Type Virus but Not BHV-1 gE Deletion Mutant Virus

Bovine herpesvirus 1 (BHV-1), an alphaherpesvirus, is a major pathogen that causes respiratory and reproductive infections. We observed tyrosine phosphorylation of a 95-kDa viral protein and dephosphorylation of 55- and 103-kDa cellular proteins during the course of BHV-1 infection. We demonstrated...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2000-03, Vol.268 (1), p.159-166
Hauptverfasser:	Shaw, A.M., Braun, L., Frew, T., Hurley, D.J., Rowland, R.R.R., Chase, C.C.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bovine herpesvirus 1 Capsid - metabolism Cell Line Dogs Gene Deletion genistein Genistein - pharmacology glycoprotein E Herpesvirus 1, Bovine - genetics Herpesvirus 1, Bovine - physiology MDBK cells Mutation Phosphorylation - drug effects Phosphotyrosine - metabolism Precipitin Tests Protein-Tyrosine Kinases - antagonists & inhibitors Quinazolines tyrosine tyrphostin AG1478 Tyrphostins - pharmacology Viral Envelope Proteins - genetics Viral Envelope Proteins - metabolism Viral Proteins Virus Replication - physiology
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