Shorter telomeres in dystrophic muscle consistent with extensive regeneration in young children

Muscular dystrophies are characterised by continuous cycles of degeneration and regeneration resulting in an eventual diminution of the muscle mass and extensive fibrosis. In somatic cells chromosomal telomeres shorten with each round of cell division and telomere length is considered to be a biomar...

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Veröffentlicht in:	Neuromuscular disorders : NMD 2000-02, Vol.10 (2), p.113-120
Hauptverfasser:	Decary, S, Hamida, C B, Mouly, V, Barbet, J P, Hentati, F, Butler-Browne, G S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Cell Division - genetics Cellular Senescence - genetics Child Child, Preschool Female Humans Male Muscle, Skeletal - pathology Muscular Dystrophies - genetics Muscular Dystrophies - pathology Regeneration - genetics Telomere - genetics Telomere - pathology
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