Dual CCK-A and CCK-B Receptor Antagonists (II). Preparation and Structure Activity Relationships of 5-Alkyl-9-methyl-1, 4-benzodiazepines and Discovery of FR208419

In our continuing research for dual CCK-A and -B antagonists, according to our hypothesis that dual CCK-A and -B antagonists should be more efficacious than selective CCK-A antagonists for the treatment of panreatitis, we have prepared various 5-alkyl-9-methyl-1, 4-benzodiazepines. From the compound...

Ausführliche Beschreibung