Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

This review documents the changing perspectives on the function of fatty-acid synthase and fatty-acid synthesis in human tumor biology. With the recent discovery that human cancer cells express high levels of fatty-acid synthase and undergo significant endogenous fatty-acid synthesis, our understand...

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Veröffentlicht in:	Nutrition 2000-03, Vol.16 (3), p.202-208
1. Verfasser:	Kuhajda, Francis P
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences cancer Cell Cycle cerulenin Enzyme Inhibitors - therapeutic use Fatty Acid Synthases - antagonists & inhibitors Fatty Acid Synthases - physiology Fatty Acids - biosynthesis fatty-acid synthase fatty-acid synthesis General aspects Glycolysis Humans Medical sciences Neoplasms - drug therapy Neoplasms - enzymology Neoplasms - pathology Tumors
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