In vitro hormone induction of final oocyte maturation in striped bass (Morone saxatilis) follicles is inhibited by blockers of phosphatidylinositol 3-kinase activity

Oocyte germinal vesicle breakdown (GVBD) was induced in striped bass ovarian fragments when tissues were incubated with 100-nM recombinant human insulin-like growth factor-I (rhIGF-I), 25-IU human chorionic gonadotropin (hCG) ml−1, or 290 nM of the maturation-inducing steroid (MIS), 17,20β,21-trihyd...

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Veröffentlicht in:	Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 2001-06, Vol.129 (2-3), p.467-473
Hauptverfasser:	Weber, G.M., Sullivan, C.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstadienes - pharmacology Animals Bass - physiology Chorionic Gonadotropin - pharmacology Chromones - pharmacology Enzyme Inhibitors - pharmacology Female Gap junction Gap Junctions - drug effects Gonadotropin Humans Insulin-like growth factor Insulin-Like Growth Factor I - pharmacology LY 294002 Marine Maturation inducing steroid Meiosis Morone saxatilis Morpholines - pharmacology Oocyte development Oocytes - cytology Oocytes - drug effects Oocytes - enzymology Oocytes - growth & development Phosphatidylinositol 3-kinase Phosphatidylinositol 3-Kinases - antagonists & inhibitors Phosphatidylinositol 3-Kinases - metabolism Signal transduction Wortmannin
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