Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins

Catheter-based percutaneous transluminal gene delivery (PTGD) into the coronary artery still falls behind the expectations of an efficient myocardial gene delivery system. In this study gene delivery was applied by selective pressure-regulated retroinfusion through the coronary veins to prolong adhe...

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Veröffentlicht in:	Gene therapy 2000-02, Vol.7 (3), p.232-240
Hauptverfasser:	Boekstegers, P, von Degenfeld, G, Giehrl, W, Heinrich, D, Hullin, R, Kupatt, C, Steinbeck, G, Baretton, G, Middeler, G, Katus, H, Franz, W M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenovirus Animals beta-Galactosidase - metabolism Cardiomyocytes Catheters Coronary artery Coronary Vessels - chemistry Expression vectors Gene expression Gene transfer Gene Transfer Techniques Genetic Vectors - genetics Immunohistochemistry Infusions, Intravenous Ischemia Myocardial Ischemia - genetics Myocardium Myocardium - chemistry Myocardium - metabolism Polymerase Chain Reaction Reporter gene Rous sarcoma virus Swine Time Factors Transfection Transfection - genetics Veins Veins & arteries β-Galactosidase
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