Interferons α and β as Immune Regulators—A New Look

The type 1 interferons, alpha and beta (IFN- alpha / beta ), are comprised of the products of multiple (up to 12) IFN- alpha genes and a single IFN- beta gene. These factors use a common heterodimeric receptor, broadly expressed on most cells. The major pathway of intracellular signaling used by IFN...

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Veröffentlicht in:	Immunity 2001-06, Vol.14 (6), p.661-664
1. Verfasser:	Biron, Christine A
Format:	Artikel
Sprache:	eng
Schlagworte:	a-Interferon Animals b-Interferon Dendritic Cells - immunology Gene Expression Regulation Humans Interferon-alpha - genetics Interferon-alpha - immunology Interferon-beta - genetics Interferon-beta - immunology Interferon-gamma - biosynthesis Interleukin-12 - genetics Interleukin-12 - immunology Interleukin-15 - biosynthesis Killer Cells, Natural - immunology
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