Parental Psychopathology and Reports of the Childhood Home Environment in Adults with Early-Onset Dysthymic Disorder

In previous studies, patients with dysthymic disorder (DD) have reported significantly more adverse early home environments than patients with episodic major depressive disorder (MDD) and normal controls. However, DD is also associated with increased rates of mood and personality disorders in first-...

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Veröffentlicht in:The journal of nervous and mental disease 2000-02, Vol.188 (2), p.63-70
Hauptverfasser: LIZARDI, HUMBERTO, KLEIN, DANIEL N
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description In previous studies, patients with dysthymic disorder (DD) have reported significantly more adverse early home environments than patients with episodic major depressive disorder (MDD) and normal controls. However, DD is also associated with increased rates of mood and personality disorders in first-degree relatives, raising the possibility that the DD-early adversity relationship may be due to the confounding effects of parental psychopathology. The present study addressed this issue using a sample of 97 adult outpatients with early-onset DD, 45 adult outpatients with episodic MDD, and 45 normal controls, and their first-degree relatives. The early home environment was assessed with semi-structured interviews and self-report inventories. Parental psychopathology was assessed using semi-structured direct and family history interviews, and diagnoses were assigned using the best-estimate procedure. Results indicated that parental mood and personality disorders were strongly associated with probands' reports of early adversity. However, patients with DD continued to differ significantly from patients with episodic MDD and normal controls after controlling for parental psychopathology.
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However, DD is also associated with increased rates of mood and personality disorders in first-degree relatives, raising the possibility that the DD-early adversity relationship may be due to the confounding effects of parental psychopathology. The present study addressed this issue using a sample of 97 adult outpatients with early-onset DD, 45 adult outpatients with episodic MDD, and 45 normal controls, and their first-degree relatives. The early home environment was assessed with semi-structured interviews and self-report inventories. Parental psychopathology was assessed using semi-structured direct and family history interviews, and diagnoses were assigned using the best-estimate procedure. Results indicated that parental mood and personality disorders were strongly associated with probands' reports of early adversity. 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source MEDLINE; Journals@Ovid Ovid Autoload
subjects Adolescent
Adult
Adult and adolescent clinical studies
Age of Onset
Ambulatory Care
Biological and medical sciences
Child
Child Abuse - psychology
Child Abuse - statistics & numerical data
Child of Impaired Parents
Depression
Dysthymic Disorder - diagnosis
Dysthymic Disorder - epidemiology
Dysthymic Disorder - psychology
Female
Humans
Male
Medical sciences
Mental Disorders - diagnosis
Mental Disorders - epidemiology
Mental Disorders - psychology
Mood disorders
Parent-Child Relations
Parenting
Parents - psychology
Personality Inventory
Psychiatric Status Rating Scales
Psychology, Child
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Social Environment
title Parental Psychopathology and Reports of the Childhood Home Environment in Adults with Early-Onset Dysthymic Disorder
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