Ibuprofen Use to Reduce the Incidence and Severity of Bronchopulmonary Dysplasia: A Pilot Study

OBJECTIVE: To assess the safety and efficacy of ibuprofen in reducing the incidence and severity of bronchopulmonary dysplasia (BPD) in preterm infants. METHODS: A total of 18 premature infants between 23 and 28 weeks’ gestation were studied. Ibuprofen (10 mg/kg of loading dose followed by 5 mg/kg e...

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Veröffentlicht in:	Journal of perinatology 2000-02, Vol.20 (1), p.13-16
Hauptverfasser:	Raju, N Venkata, Bharadwaj, Radha A, Thomas, Ronald, Konduri, Ganesh G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aminophylline Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Bronchopulmonary Dysplasia - diagnosis Bronchopulmonary Dysplasia - drug therapy Bronchopulmonary Dysplasia - epidemiology Complications Dose-Response Relationship, Drug Drug Administration Schedule Drug therapy Dysplasia Enterocolitis Female Follow-Up Studies Gastrointestinal diseases Hemorrhage Humans Ibuprofen Ibuprofen - administration & dosage Incidence Infant, Newborn Infant, Premature, Diseases - diagnosis Infant, Premature, Diseases - drug therapy Infant, Premature, Diseases - epidemiology Infants Injections, Intravenous Lung diseases Male Medicine Medicine & Public Health Necrosis Necrotizing enterocolitis Neonates Newborn babies Nonsteroidal anti-inflammatory drugs original-article Pediatric Surgery Pediatrics Pilot Projects Plasma levels Premature babies Renal failure Severity of Illness Index Statistics, Nonparametric Steroid hormones Steroids Treatment Outcome
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