Right ventricular form and function after percutaneous atrial septal defect device closure
OBJECTIVES We sought to assess the right heart’s response to percutaneous device closure of moderate sized atrial septal defects (ASDs) in adults over a one-year follow-up period. BACKGROUND Percutaneous ASD device closure is a safe and effective means of reducing or eliminating interatrial shunting...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2001-06, Vol.37 (8), p.2108-2113 |
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| creator | Veldtman, Gruschen R Razack, Vanessa Siu, Samuel El-Hajj, Hassan Walker, Fiona Webb, Gary D Benson, Leland N McLaughlin, Peter R |
| description | OBJECTIVES
We sought to assess the right heart’s response to percutaneous device closure of moderate sized atrial septal defects (ASDs) in adults over a one-year follow-up period.
BACKGROUND
Percutaneous ASD device closure is a safe and effective means of reducing or eliminating interatrial shunting. The response of the adult’s right heart to device closure is incompletely understood.
METHODS
Forty consecutive patients had 40 device implantations (32 with the CardioSeal implant and 8 with the Amplatzer device). The patients were assessed with echocardiography, chest radiography and electrocardiography before the procedure and at 1, 6 and 12 months.
RESULTS
The mean ASD size was 13 ± 4 mm, and the device size ranged from 33 to 40 mm for CardioSeal and 12 to 36 mm for Amplatzer. At one month, heart size (49% vs. 46%), four-chamber right ventricular (RV) size (45 vs. 41 mm), paradoxical septal motion (60% vs. 5%), QRS duration (125 vs. 119 ms), PR interval (181 vs. 155 ms) and echocardiographically determined pulmonary artery systolic pressure decreased significantly and was maintained at 12-month follow-up. At six months, right atrial length decreased from 50 to 47 mm. At one year, 29% of patients had persistent RV enlargement.
CONCLUSIONS
Right heart morphology undergoes rapid improvement within one month of defect closure, with associated mechanoelectrical benefit. A small number of patients had persistent RV enlargement or pulmonary hypertension, or both, at one year. Our data support the application of transcatheter methods in achieving excellent hemodynamic and anatomic outcomes. |
| doi_str_mv | 10.1016/S0735-1097(01)01305-5 |
| format | Article |
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We sought to assess the right heart’s response to percutaneous device closure of moderate sized atrial septal defects (ASDs) in adults over a one-year follow-up period.
BACKGROUND
Percutaneous ASD device closure is a safe and effective means of reducing or eliminating interatrial shunting. The response of the adult’s right heart to device closure is incompletely understood.
METHODS
Forty consecutive patients had 40 device implantations (32 with the CardioSeal implant and 8 with the Amplatzer device). The patients were assessed with echocardiography, chest radiography and electrocardiography before the procedure and at 1, 6 and 12 months.
RESULTS
The mean ASD size was 13 ± 4 mm, and the device size ranged from 33 to 40 mm for CardioSeal and 12 to 36 mm for Amplatzer. At one month, heart size (49% vs. 46%), four-chamber right ventricular (RV) size (45 vs. 41 mm), paradoxical septal motion (60% vs. 5%), QRS duration (125 vs. 119 ms), PR interval (181 vs. 155 ms) and echocardiographically determined pulmonary artery systolic pressure decreased significantly and was maintained at 12-month follow-up. At six months, right atrial length decreased from 50 to 47 mm. At one year, 29% of patients had persistent RV enlargement.
CONCLUSIONS
Right heart morphology undergoes rapid improvement within one month of defect closure, with associated mechanoelectrical benefit. A small number of patients had persistent RV enlargement or pulmonary hypertension, or both, at one year. Our data support the application of transcatheter methods in achieving excellent hemodynamic and anatomic outcomes.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/S0735-1097(01)01305-5</identifier><identifier>PMID: 11419895</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cardiac Catheterization ; Diseases of the cardiovascular system ; Female ; Heart Septal Defects, Atrial - pathology ; Heart Septal Defects, Atrial - surgery ; Heart Ventricles - pathology ; Humans ; Male ; Medical sciences ; Middle Aged ; Postoperative Period ; Prostheses and Implants ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Retrospective Studies ; Ventricular Function, Right</subject><ispartof>Journal of the American College of Cardiology, 2001-06, Vol.37 (8), p.2108-2113</ispartof><rights>2001 American College of Cardiology</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-b6b46bc9dea27a20f719cf4e94e56f23c1fa6cd2d9de75000ee6e5fd558fd2703</citedby><cites>FETCH-LOGICAL-c538t-b6b46bc9dea27a20f719cf4e94e56f23c1fa6cd2d9de75000ee6e5fd558fd2703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0735-1097(01)01305-5$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1046036$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11419895$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Veldtman, Gruschen R</creatorcontrib><creatorcontrib>Razack, Vanessa</creatorcontrib><creatorcontrib>Siu, Samuel</creatorcontrib><creatorcontrib>El-Hajj, Hassan</creatorcontrib><creatorcontrib>Walker, Fiona</creatorcontrib><creatorcontrib>Webb, Gary D</creatorcontrib><creatorcontrib>Benson, Leland N</creatorcontrib><creatorcontrib>McLaughlin, Peter R</creatorcontrib><title>Right ventricular form and function after percutaneous atrial septal defect device closure</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>OBJECTIVES
We sought to assess the right heart’s response to percutaneous device closure of moderate sized atrial septal defects (ASDs) in adults over a one-year follow-up period.
BACKGROUND
Percutaneous ASD device closure is a safe and effective means of reducing or eliminating interatrial shunting. The response of the adult’s right heart to device closure is incompletely understood.
METHODS
Forty consecutive patients had 40 device implantations (32 with the CardioSeal implant and 8 with the Amplatzer device). The patients were assessed with echocardiography, chest radiography and electrocardiography before the procedure and at 1, 6 and 12 months.
RESULTS
The mean ASD size was 13 ± 4 mm, and the device size ranged from 33 to 40 mm for CardioSeal and 12 to 36 mm for Amplatzer. At one month, heart size (49% vs. 46%), four-chamber right ventricular (RV) size (45 vs. 41 mm), paradoxical septal motion (60% vs. 5%), QRS duration (125 vs. 119 ms), PR interval (181 vs. 155 ms) and echocardiographically determined pulmonary artery systolic pressure decreased significantly and was maintained at 12-month follow-up. At six months, right atrial length decreased from 50 to 47 mm. At one year, 29% of patients had persistent RV enlargement.
CONCLUSIONS
Right heart morphology undergoes rapid improvement within one month of defect closure, with associated mechanoelectrical benefit. A small number of patients had persistent RV enlargement or pulmonary hypertension, or both, at one year. Our data support the application of transcatheter methods in achieving excellent hemodynamic and anatomic outcomes.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiac Catheterization</subject><subject>Diseases of the cardiovascular system</subject><subject>Female</subject><subject>Heart Septal Defects, Atrial - pathology</subject><subject>Heart Septal Defects, Atrial - surgery</subject><subject>Heart Ventricles - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Postoperative Period</subject><subject>Prostheses and Implants</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Retrospective Studies</subject><subject>Ventricular Function, Right</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LJDEQhoOs6PjxE5QcFtFDa9LppCenZRG_QBD8uHgJmUrFzdLTPZukB_z3RmdYvXl6L0-9VfUQcsDZKWdcnT2wVsiKM90eM37CuGCykhtkwqWcVkLq9geZ_Ee2yU5Kfxljasr1FtnmvOF6quWEPN-Hlz-ZLrHPMcDY2Uj9EOfU9o76sYcchp5anzHSBUYYs-1xGBO1BbcdTbjIJRx6hFxiGQApdEMaI-6RTW-7hPvr3CVPlxeP59fV7d3Vzfnv2wqkmOZqpmaNmoF2aOvW1sy3XINvUDcola8FcG8VuNoVopXlB0SF0rvyp3d1y8QuOVr1LuLwb8SUzTwkwK5bnWpapoXSoimgXIEQh5QierOIYW7jq-HMvEs1H1LNuzHDuPmQamSZO1wvGGdzdJ9Ta4sF-LkGbALb-Wh7COlLe6OYUAX7tcKw2FgGjCZBwB7QhVj0GTeEby55A7T9lU0</recordid><startdate>20010615</startdate><enddate>20010615</enddate><creator>Veldtman, Gruschen R</creator><creator>Razack, Vanessa</creator><creator>Siu, Samuel</creator><creator>El-Hajj, Hassan</creator><creator>Walker, Fiona</creator><creator>Webb, Gary D</creator><creator>Benson, Leland N</creator><creator>McLaughlin, Peter R</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010615</creationdate><title>Right ventricular form and function after percutaneous atrial septal defect device closure</title><author>Veldtman, Gruschen R ; Razack, Vanessa ; Siu, Samuel ; El-Hajj, Hassan ; Walker, Fiona ; Webb, Gary D ; Benson, Leland N ; McLaughlin, Peter R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-b6b46bc9dea27a20f719cf4e94e56f23c1fa6cd2d9de75000ee6e5fd558fd2703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiac Catheterization</topic><topic>Diseases of the cardiovascular system</topic><topic>Female</topic><topic>Heart Septal Defects, Atrial - pathology</topic><topic>Heart Septal Defects, Atrial - surgery</topic><topic>Heart Ventricles - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Postoperative Period</topic><topic>Prostheses and Implants</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Retrospective Studies</topic><topic>Ventricular Function, Right</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Veldtman, Gruschen R</creatorcontrib><creatorcontrib>Razack, Vanessa</creatorcontrib><creatorcontrib>Siu, Samuel</creatorcontrib><creatorcontrib>El-Hajj, Hassan</creatorcontrib><creatorcontrib>Walker, Fiona</creatorcontrib><creatorcontrib>Webb, Gary D</creatorcontrib><creatorcontrib>Benson, Leland N</creatorcontrib><creatorcontrib>McLaughlin, Peter R</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Veldtman, Gruschen R</au><au>Razack, Vanessa</au><au>Siu, Samuel</au><au>El-Hajj, Hassan</au><au>Walker, Fiona</au><au>Webb, Gary D</au><au>Benson, Leland N</au><au>McLaughlin, Peter R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Right ventricular form and function after percutaneous atrial septal defect device closure</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2001-06-15</date><risdate>2001</risdate><volume>37</volume><issue>8</issue><spage>2108</spage><epage>2113</epage><pages>2108-2113</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>OBJECTIVES
We sought to assess the right heart’s response to percutaneous device closure of moderate sized atrial septal defects (ASDs) in adults over a one-year follow-up period.
BACKGROUND
Percutaneous ASD device closure is a safe and effective means of reducing or eliminating interatrial shunting. The response of the adult’s right heart to device closure is incompletely understood.
METHODS
Forty consecutive patients had 40 device implantations (32 with the CardioSeal implant and 8 with the Amplatzer device). The patients were assessed with echocardiography, chest radiography and electrocardiography before the procedure and at 1, 6 and 12 months.
RESULTS
The mean ASD size was 13 ± 4 mm, and the device size ranged from 33 to 40 mm for CardioSeal and 12 to 36 mm for Amplatzer. At one month, heart size (49% vs. 46%), four-chamber right ventricular (RV) size (45 vs. 41 mm), paradoxical septal motion (60% vs. 5%), QRS duration (125 vs. 119 ms), PR interval (181 vs. 155 ms) and echocardiographically determined pulmonary artery systolic pressure decreased significantly and was maintained at 12-month follow-up. At six months, right atrial length decreased from 50 to 47 mm. At one year, 29% of patients had persistent RV enlargement.
CONCLUSIONS
Right heart morphology undergoes rapid improvement within one month of defect closure, with associated mechanoelectrical benefit. A small number of patients had persistent RV enlargement or pulmonary hypertension, or both, at one year. Our data support the application of transcatheter methods in achieving excellent hemodynamic and anatomic outcomes.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11419895</pmid><doi>10.1016/S0735-1097(01)01305-5</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0735-1097 |
| ispartof | Journal of the American College of Cardiology, 2001-06, Vol.37 (8), p.2108-2113 |
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| subjects | Adult Aged Biological and medical sciences Cardiac Catheterization Diseases of the cardiovascular system Female Heart Septal Defects, Atrial - pathology Heart Septal Defects, Atrial - surgery Heart Ventricles - pathology Humans Male Medical sciences Middle Aged Postoperative Period Prostheses and Implants Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Retrospective Studies Ventricular Function, Right |
| title | Right ventricular form and function after percutaneous atrial septal defect device closure |
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