Induction of Cholinergic Function in Cultured Sympathetic Neurons by Periosteal Cells: Cellular Mechanisms

Periosteum, the connective tissue surrounding bone, alters the transmitter properties of its sympathetic innervation during development in vivo and after transplantation. Initial noradrenergic properties are downregulated and the innervation acquires cholinergic and peptidergic properties. To elucid...

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Veröffentlicht in:	Developmental biology 2001-07, Vol.235 (1), p.1-11
Hauptverfasser:	Asmus, Stephen E., Tian, Hua, Landis, Story C.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Animals, Newborn autonomic neurons Cell Adhesion Cells, Cultured Choline O-Acetyltransferase - metabolism cholinergic Ciliary Neurotrophic Factor - genetics Ciliary Neurotrophic Factor - physiology CNTF Coculture Techniques Culture Media, Conditioned Growth Inhibitors - genetics Growth Inhibitors - physiology Interleukin-6 Leukemia Inhibitory Factor Leukemia Inhibitory Factor Receptor alpha Subunit LIF Lymphokines - genetics Lymphokines - physiology Mice Neurons - cytology Neurons - enzymology Neurons - metabolism noradrenergic osteoblast Osteoblasts - cytology periosteum Rats Receptors, Cholinergic - metabolism Receptors, Cytokine - metabolism Receptors, OSM-LIF Signal Transduction Sympathetic Nervous System - enzymology sympathetic neurons
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