Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas

Considering the role in the metabolism of chemicals played by biotransformation enzymes, we aimed at determining whether any association exists between genetic polymorphisms in CYP1A1, CYP2E1, epoxide hydrolase (EPHX), glutathione S-transferases (GSTM1/P1/T1) and individual susceptibility to lymphom...

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Veröffentlicht in:	Human molecular genetics 2001-06, Vol.10 (12), p.1265-1273
Hauptverfasser:	SARMANOVA, Jana, BENESOVA, Katerina, GUT, Ivan, NEDELCHEVA-KRISTENSEN, Vessela, TYNKOVA, Lucie, SOUCEK, Pavel
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Biotransformation Case-Control Studies CYP1A1 gene CYP2E1 gene Cytochrome P-450 CYP1A1 - genetics Cytochrome P-450 CYP2E1 - genetics Cytochrome P-450 Enzyme System - genetics Epoxide Hydrolases - genetics Exons Female Genetic Predisposition to Disease Genotype Glutathione Transferase - genetics GSTM1 gene GSTP1 gene GSTT1 gene Hematologic and hematopoietic diseases Hodgkin Disease - enzymology Hodgkin Disease - genetics Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Non-Hodgkin - enzymology Lymphoma, Non-Hodgkin - genetics Male Medical sciences Middle Aged non-Hodgkin's lymphoma Polymorphism, Genetic
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