Expression of cathepsin L and its endogenous inhibitors in immortal and transformed fibroblasts

Methods: The activities of cathepsin L and its endogenous inhibitors were analyzed in rat embryo fibroblasts, immortalized and transformed by different genes. Results: Regardless of the transfecting agent used (DNA of adenovirus SA7 or polyomavirus LT gene), the immortal cells showed an increase in...

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Veröffentlicht in:	Clinica chimica acta 2001-07, Vol.309 (1), p.37-43
Hauptverfasser:	Dilakyan, E.A, Zhurbitskaya, V.A, Vinokurova, S.V, Gureeva, T.A, Lubkova, O.N, Topol, L.Z, Kisseljov, F.L, Solovyeva, N.I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus E1A Proteins - genetics Adenoviruses, Simian - genetics Animals Cathepsin L Cathepsins - antagonists & inhibitors Cathepsins - biosynthesis Cathepsins - genetics Cell Line, Transformed - cytology Cell Line, Transformed - metabolism Cysteine Endopeptidases Cysteine Proteinase Inhibitors - metabolism DNA - genetics Embryo, Mammalian - cytology Endogenous inhibitor Enzyme Inhibitors - metabolism Enzyme Inhibitors - pharmacology Fibroblasts - cytology Fibroblasts - metabolism Gene Genes, ras - genetics Immortalization Rats Transfection Transformation
Online-Zugang:	Volltext
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