ALK1 and p80 Expression and Chromosomal Rearrangements Involving 2p23 in Inflammatory Myofibroblastic Tumor

Background: Inflammatory myofibroblastic tumor (IMT) is an uncommon tumor of extrapulmonary and pulmonary tissues with an unpredictable clinical course, occasional recurrences, and rare malignant transformation. Clonal abnormalities with rearrangements of chromosome of 2p23 and the ALK gene have bee...

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Veröffentlicht in:	Modern pathology 2001-06, Vol.14 (6), p.569-576
Hauptverfasser:	Coffin, Cheryl M, Patel, Ankita, Perkins, Sherrie, Elenitoba-Johnson, Kojo S J, Perlman, Elizabeth, Griffin, Constance A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adolescent Adult ALK gene rearrangements ALK immunohisto-chemistry Antibodies Child Child, Preschool Chromosomes Chromosomes, Human, Pair 2 - genetics Female Gene Expression Regulation, Neoplastic Granuloma, Plasma Cell - genetics Granuloma, Plasma Cell - metabolism Granuloma, Plasma Cell - pathology Humans Hybridization Immunohistochemistry In Situ Hybridization, Fluorescence Infant Infant, Newborn Inflammatory myofibroblastic tumor Kinases Laboratory Medicine Lymphoma Male Medicine Medicine & Public Health original-article Pathology Protein-Tyrosine Kinases - analysis Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases Translocation, Genetic Tumors
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