Anticoagulant properties of dextranmethylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive functionalized dextran

Dextranmethylcarboxylate benzylamide sulfate (DMCBSu), a functionalized dextran, exhibits anticoagulant properties. Its synthesis involves three steps: a carboxymethylation with monochloroacetic acid in alkaline water–isopropanol, a benzylamidification of some of the methylcarboxylate groups with be...

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Veröffentlicht in:	Carbohydrate research 2001-05, Vol.332 (1), p.75-83
Hauptverfasser:	Huynh, Rémi, Chaubet, Frédéric, Jozefonvicz, Jacqueline
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulant activities Anticoagulants - chemical synthesis Anticoagulants - pharmacology Benzyl Compounds - chemical synthesis Benzyl Compounds - pharmacology Chromatography - methods Dextran derivatives Dextrans - chemical synthesis Dextrans - pharmacology Heparin - pharmacology Humans Ions Polysaccharides Random functionalization Spectroscopy, Fourier Transform Infrared
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