The Role of Protein C, Protein S, and Resistance to Activated Protein C in Legg-Perthes Disease

It has been hypothesized that Legg-Perthes disease is caused by repeated vascular interruptions of the blood supply to the proximal femur, which are precipitated by coagulation system abnormalities. To test this theory, we conducted a case-control study among 57 patients with Legg-Perthes disease an...

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Veröffentlicht in:	Pediatrics (Evanston) 2001-06, Vol.107 (6), p.1329-1334
Hauptverfasser:	Eldridge, John, Dilley, Anne, Austin, Harland, EL-Jamil, Muhydine, Wolstein, Lori, Doris, John, Hooper, W. Craig, Meehan, Peter L, Evatt, Bruce
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated Protein C Resistance - physiopathology Adolescent Adult Biological and medical sciences Blood clotting disorders Blood coagulation disorders Blood Coagulation Tests Causes of Child Child, Preschool Disease Diseases of the osteoarticular system Factor V - genetics Female Genetics Hip joint Humans Legg-Calve-Perthes disease Legg-Calve-Perthes Disease - blood Legg-Calve-Perthes Disease - genetics Legg-Calve-Perthes Disease - physiopathology Male Medical sciences Pediatrics Point Mutation - genetics Protein C - analysis Protein C - physiology Protein S - analysis Protein S - physiology Proteins Risk Factors Vascular bone diseases
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