Repression of myosin isoforms in developing and denervated skeletal muscle fibers originates near motor endplates

During development of chicken pectoralis muscle, a neonatal myosin heavy‐chain isoform is supplanted progressively by an adult isoform. This expression is under neuronal control. In this study we test the hypothesis that developmental myosin transformations are initiated near the motor endplate of e...

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Veröffentlicht in:	Developmental dynamics 2000-01, Vol.217 (1), p.50-61
Hauptverfasser:	Rosser, Benjamin W. C., Farrar, Cindy M., Crellin, Natasha K., Andersen, Linda B., Bandman, Everett
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chickens denervate Denervation Down-Regulation end plate Gene Expression Regulation, Developmental Motor Endplate - cytology Motor Endplate - physiology muscle Muscle, Skeletal - cytology Muscle, Skeletal - innervation Muscle, Skeletal - physiology myosin Myosin Heavy Chains - biosynthesis Myosin Heavy Chains - genetics Protein Isoforms - biosynthesis Protein Isoforms - genetics
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