Expression, Purification, and Characterization of Human Recombinant Thrombopoietin in Chinese Hamster Ovary Cells

Thrombopoietin (TPO) is a primary regulator of megakaryocytopoiesis, a process through which megakaryocytes proliferate and mature into platelets. Recombinant human TPO (rhTPO) was expressed in Chinese hamster ovary (CHO) cells and purified from the culture medium. The cDNA encoding full-length TPO,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Protein expression and purification 2000-03, Vol.18 (2), p.213-220
Hauptverfasser:	Kaszubska, Wiweka, Zhang, Haiying, Patterson, Robert L., Suhar, Thomas S., Uchic, Marie E., Dickinson, Robert W., Schaefer, Verlyn G., Haasch, Deanna, Janis, Richard S., DeVries, Peter J., Okasinski, Gregory F., Meuth, Joseph L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cell Division - drug effects Cell Line CHO Cells Cricetinae Electrophoresis, Polyacrylamide Gel Hematocrit Humans Male Mice Mice, Inbred BALB C Platelet Count Receptors, Granulocyte Colony-Stimulating Factor - metabolism Recombinant Proteins - genetics Recombinant Proteins - metabolism Recombinant Proteins - pharmacology Signal Transduction - physiology Thrombopoietin - genetics Thrombopoietin - metabolism Thrombopoietin - pharmacology Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!