Intrathecal baclofen for generalized dystonia: A case report
Jaffe MS, Nienstedt LJ. Intrathecal baclofen forgeneralized dystonia: a case report. Arch Phys Med Rehabil 2001;82:853-5. Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dy...
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| Veröffentlicht in: | Archives of physical medicine and rehabilitation 2001-06, Vol.82 (6), p.853-855 |
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| container_title | Archives of physical medicine and rehabilitation |
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| creator | Jaffe, Michael S. Nienstedt, Linda J. |
| description | Jaffe MS, Nienstedt LJ. Intrathecal baclofen forgeneralized dystonia: a case report. Arch Phys Med Rehabil 2001;82:853-5. Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dystonia usually evolves to a debilitating condition, often unresponsive to oral pharmacologic regimens or physical rehabilitation. We present the case of a patient with idiopathic adult-onset generalized dystonia who was recalcitrant to oral therapies. This patient was treated with intrathecal baclofen therapy and responded dramatically with improved functional abilities, resolution of chronic pain, and an improved rating on the dystonia scale. |
| doi_str_mv | 10.1053/apmr.2001.23268 |
| format | Article |
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Intrathecal baclofen forgeneralized dystonia: a case report. Arch Phys Med Rehabil 2001;82:853-5. Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dystonia usually evolves to a debilitating condition, often unresponsive to oral pharmacologic regimens or physical rehabilitation. We present the case of a patient with idiopathic adult-onset generalized dystonia who was recalcitrant to oral therapies. This patient was treated with intrathecal baclofen therapy and responded dramatically with improved functional abilities, resolution of chronic pain, and an improved rating on the dystonia scale.</description><identifier>ISSN: 0003-9993</identifier><identifier>EISSN: 1532-821X</identifier><identifier>DOI: 10.1053/apmr.2001.23268</identifier><identifier>PMID: 11387595</identifier><identifier>CODEN: APMHAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Baclofen ; Baclofen - therapeutic use ; Biological and medical sciences ; Bones, joints and connective tissue. Antiinflammatory agents ; Case report ; Dystonia ; Dystonia - drug therapy ; Dystonia - rehabilitation ; GABA Agonists - therapeutic use ; Humans ; Infusion Pumps, Implantable ; Injections, Spinal ; Male ; Medical sciences ; Muscle Relaxants, Central - therapeutic use ; Pharmacology. 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Intrathecal baclofen forgeneralized dystonia: a case report. Arch Phys Med Rehabil 2001;82:853-5. Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dystonia usually evolves to a debilitating condition, often unresponsive to oral pharmacologic regimens or physical rehabilitation. We present the case of a patient with idiopathic adult-onset generalized dystonia who was recalcitrant to oral therapies. This patient was treated with intrathecal baclofen therapy and responded dramatically with improved functional abilities, resolution of chronic pain, and an improved rating on the dystonia scale.</description><subject>Aged</subject><subject>Baclofen</subject><subject>Baclofen - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Bones, joints and connective tissue. Antiinflammatory agents</subject><subject>Case report</subject><subject>Dystonia</subject><subject>Dystonia - drug therapy</subject><subject>Dystonia - rehabilitation</subject><subject>GABA Agonists - therapeutic use</subject><subject>Humans</subject><subject>Infusion Pumps, Implantable</subject><subject>Injections, Spinal</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle Relaxants, Central - therapeutic use</subject><subject>Pharmacology. 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Antiinflammatory agents</topic><topic>Case report</topic><topic>Dystonia</topic><topic>Dystonia - drug therapy</topic><topic>Dystonia - rehabilitation</topic><topic>GABA Agonists - therapeutic use</topic><topic>Humans</topic><topic>Infusion Pumps, Implantable</topic><topic>Injections, Spinal</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscle Relaxants, Central - therapeutic use</topic><topic>Pharmacology. Drug treatments</topic><topic>Rehabilitation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jaffe, Michael S.</creatorcontrib><creatorcontrib>Nienstedt, Linda J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of physical medicine and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jaffe, Michael S.</au><au>Nienstedt, Linda J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intrathecal baclofen for generalized dystonia: A case report</atitle><jtitle>Archives of physical medicine and rehabilitation</jtitle><addtitle>Arch Phys Med Rehabil</addtitle><date>2001-06-01</date><risdate>2001</risdate><volume>82</volume><issue>6</issue><spage>853</spage><epage>855</epage><pages>853-855</pages><issn>0003-9993</issn><eissn>1532-821X</eissn><coden>APMHAI</coden><abstract>Jaffe MS, Nienstedt LJ. Intrathecal baclofen forgeneralized dystonia: a case report. Arch Phys Med Rehabil 2001;82:853-5. Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dystonia usually evolves to a debilitating condition, often unresponsive to oral pharmacologic regimens or physical rehabilitation. We present the case of a patient with idiopathic adult-onset generalized dystonia who was recalcitrant to oral therapies. This patient was treated with intrathecal baclofen therapy and responded dramatically with improved functional abilities, resolution of chronic pain, and an improved rating on the dystonia scale.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11387595</pmid><doi>10.1053/apmr.2001.23268</doi><tpages>3</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Baclofen Baclofen - therapeutic use Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Case report Dystonia Dystonia - drug therapy Dystonia - rehabilitation GABA Agonists - therapeutic use Humans Infusion Pumps, Implantable Injections, Spinal Male Medical sciences Muscle Relaxants, Central - therapeutic use Pharmacology. Drug treatments Rehabilitation |
| title | Intrathecal baclofen for generalized dystonia: A case report |
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