Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients
The present study evaluates the presence of oxidative stress in the uncontrolled diabetic state. Glycemic control reduced the oxidative stress, but total normalization of the parameters of oxidative stress was not achieved, indicating continued oxidant injury despite optimal control of the diabetes....
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| Veröffentlicht in: | Metabolism, clinical and experimental clinical and experimental, 2000-02, Vol.49 (2), p.160-162 |
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| container_end_page | 162 |
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| container_issue | 2 |
| container_start_page | 160 |
| container_title | Metabolism, clinical and experimental |
| container_volume | 49 |
| creator | Sharma, Anjali Kharb, Simmi Chugh, S.N. Kakkar, Rajesh Singh, G.P. |
| description | The present study evaluates the presence of oxidative stress in the uncontrolled diabetic state. Glycemic control reduced the oxidative stress, but total normalization of the parameters of oxidative stress was not achieved, indicating continued oxidant injury despite optimal control of the diabetes. Vitamin E supplementation for 4 weeks in these patients further reduced the oxidative stress, suggesting that vitamin E supplementation might be helpful in reducing free-radical—induced oxidant injury. |
| doi_str_mv | 10.1016/S0026-0495(00)91117-X |
| format | Article |
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| ispartof | Metabolism, clinical and experimental, 2000-02, Vol.49 (2), p.160-162 |
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| subjects | Adult Biological and medical sciences Blood Glucose - metabolism Diabetes Mellitus - blood Diabetes Mellitus - drug therapy Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Glipizide - therapeutic use Glutathione - blood Glyburide - therapeutic use Humans Hypoglycemic Agents - therapeutic use Male Medical sciences Middle Aged Oxidative Stress - physiology Thiobarbituric Acid Reactive Substances - metabolism Vitamin E - pharmacology |
| title | Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients |
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