Cathepsin B and its inhibitor stefin A in brain tumors

Cysteine protease cathepsin B (CatB) and its endogenous inhibitor stefin A (StA) play an important role in tumor progression. Increase of CatB expression and lower levels of its inhibitors were associated with tumor malignancy in brain tumors. In this study of 100 patients, CatB was localized by imm...

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Veröffentlicht in:	Pflügers Archiv 2000, Vol.439 (3 Suppl), p.R122-R123
Hauptverfasser:	Strojnik, T, Zajc, I, Bervar, A, Zidanik, B, Golouh, R, Kos, J, Dolenc, V, Lah, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - metabolism Brain - pathology Brain Neoplasms - metabolism Brain Neoplasms - pathology Cathepsin B - antagonists & inhibitors Cathepsin B - genetics Cathepsin B - metabolism Cystatin A Cystatins - genetics Cystatins - metabolism Cystatins - physiology Endothelium - metabolism Endothelium - pathology Glioblastoma - metabolism Glioblastoma - pathology Humans Immunohistochemistry Middle Aged Prognosis Proportional Hazards Models RNA, Messenger - metabolism Survival Analysis
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