Bilateral blindness as the initial presentation of lymphoma of the sphenoid sinus

PURPOSE: To report a patient with large-cell lymphoma of the sphenoid sinus presenting with bilateral blindness and no other signs or symptoms. METHOD: Case report. A previously healthy 5-year-old boy complained of sudden vision loss without other systemic complaints. RESULTS: Ophthalmologic examina...

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Veröffentlicht in:American journal of ophthalmology 2000-02, Vol.129 (2), p.256-258
Hauptverfasser: Roth, Daniel B, Siatkowski, R.Michael
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container_title American journal of ophthalmology
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creator Roth, Daniel B
Siatkowski, R.Michael
description PURPOSE: To report a patient with large-cell lymphoma of the sphenoid sinus presenting with bilateral blindness and no other signs or symptoms. METHOD: Case report. A previously healthy 5-year-old boy complained of sudden vision loss without other systemic complaints. RESULTS: Ophthalmologic examination revealed no light perception bilaterally. The pupils of the patient were fixed at 8 mm without reaction to the brightest light stimulus. Systemic examination was unremarkable, and neuroimaging revealed a large sphenoid tumor extending intracranially. Biopsy of the tumor proved to be large-cell lymphoma. CONCLUSION: Large-cell lymphoma affecting children may present initially with blindness, without other systemic symptoms.
doi_str_mv 10.1016/S0002-9394(99)00308-6
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METHOD: Case report. A previously healthy 5-year-old boy complained of sudden vision loss without other systemic complaints. RESULTS: Ophthalmologic examination revealed no light perception bilaterally. The pupils of the patient were fixed at 8 mm without reaction to the brightest light stimulus. Systemic examination was unremarkable, and neuroimaging revealed a large sphenoid tumor extending intracranially. Biopsy of the tumor proved to be large-cell lymphoma. CONCLUSION: Large-cell lymphoma affecting children may present initially with blindness, without other systemic symptoms.</description><subject>Biological and medical sciences</subject><subject>Blindness - diagnosis</subject><subject>Blindness - etiology</subject><subject>Child, Preschool</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. 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subjects Biological and medical sciences
Blindness - diagnosis
Blindness - etiology
Child, Preschool
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphoma, Large B-Cell, Diffuse - complications
Lymphoma, Large B-Cell, Diffuse - diagnosis
Lymphoma, Large B-Cell, Diffuse - radiotherapy
Magnetic Resonance Imaging
Male
Medical sciences
Paranasal Sinus Neoplasms - complications
Paranasal Sinus Neoplasms - diagnosis
Paranasal Sinus Neoplasms - radiotherapy
Sphenoid Sinus - pathology
Sphenoid Sinus - radiation effects
Tomography, X-Ray Computed
title Bilateral blindness as the initial presentation of lymphoma of the sphenoid sinus
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