Sleep and memory deficits in the rat produced by experimental infection with Trypanosoma cruzi

We investigated whether the infection with Trypanosoma cruzi in rats could produce functional alterations of the central nervous system. The experimental group received an injection of 150,000 trypomastigotes / rat, whereas the control group received a saline injection. Spontaneous alternation behav...

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Veröffentlicht in:	Neuroscience letters 2001-06, Vol.306 (1), p.65-68
Hauptverfasser:	Arankowsky-Sandoval, Gloria, Mut-Martı́n, Mirza, Solı́s-Rodrı́guez, Francisco, Góngora-Alfaro, José L., Barrera-Pérez, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain - parasitology Brain - pathology Brain - physiopathology Chagas Disease - complications Chagas Disease - pathology Chagas Disease - physiopathology Chagas’ disease Cholinergic Fibers - parasitology Cholinergic Fibers - pathology Experimental protozoal diseases and models Hypothalamic Area, Lateral - parasitology Hypothalamic Area, Lateral - pathology Hypothalamic Area, Lateral - physiopathology Infectious diseases Male Maze Learning - physiology Medical sciences Memory Disorders - parasitology Memory Disorders - pathology Memory Disorders - physiopathology NADPH Dehydrogenase - metabolism Nervous system Neurons - parasitology Neurons - pathology Parasitic diseases Protozoal diseases Rat Rats Rats, Wistar Septal Nuclei - parasitology Septal Nuclei - pathology Septal Nuclei - physiopathology Sleep Sleep Wake Disorders - parasitology Sleep Wake Disorders - pathology Sleep Wake Disorders - physiopathology Spontaneous alternation Tegmentum Mesencephali - parasitology Tegmentum Mesencephali - pathology Tegmentum Mesencephali - physiopathology Trypanosoma cruzi Trypanosoma cruzi - pathogenicity Trypanosoma cruzi - physiology
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