Highly Enantioselective Synthesis of α,β-Diaminopropanoic Acid Derivatives Using a Catalytic Asymmetric Hydrogenation Approach

Rh-DuPhos-catalyzed asymmetric hydrogenation of α,β-diamidoacrylates provides a highly efficient and enantioselective route to chiral α,β-diaminopropanoic acid derivatives. The mechanistic course of the hydrogenation was studied using isotopically enriched enamide complexes and phosphorus and carbon...

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Veröffentlicht in:	Journal of organic chemistry 2001-06, Vol.66 (12), p.4141-4147
Hauptverfasser:	Robinson, Andrea J, Lim, Chin Yu, He, Linnan, Ma, Philip, Li, Hui-Yin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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