A common mutation in the gene for coagulation factor XIII‐A (VAL34Leu): A risk factor for primary intracerebral hemorrhage is protective against atherothrombotic diseases

The role of a common polymorphism in the factor XIII A‐subunit gene (FXIII Val34Leu) has been recently investigated as a protective genetic factor against arterial and venous thrombosis. In addition, the less frequent Leu34 allele has been described as a risk factor for intracerebral hemorrhage. We...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of hematology 2001-07, Vol.67 (3), p.183-188
Hauptverfasser:	Gemmati, Donato, Serino, Maria L., Ongaro, Alessia, Tognazzo, Silvia, Moratelli, Stefano, Resca, Riccardo, Moretti, Mauro, Scapoli, Gian L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age of Onset Alleles Amino Acid Substitution Arteriosclerosis - epidemiology Arteriosclerosis - genetics Biological and medical sciences Case-Control Studies Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - genetics cerebrovascular disease Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - genetics Comorbidity Coronary Disease - epidemiology Coronary Disease - genetics coronary heart disease Diabetes Mellitus - epidemiology Disease Progression Factor XIII - genetics FXIII Val34Leu mutation Gene Frequency Genes Genetic Predisposition to Disease genetic protective factors genetic risk factors Genotype Hematologic and hematopoietic diseases Humans Hyperlipidemias - epidemiology Hypertension - epidemiology intracerebral hemorrhage Ischemic Attack, Transient - epidemiology Ischemic Attack, Transient - genetics Medical sciences Mutation, Missense Myocardial Infarction - epidemiology Myocardial Infarction - genetics Platelet diseases and coagulopathies Polymerase Chain Reaction Polymorphism, Genetic Protein Subunits Risk Factors Smoking - epidemiology Thrombosis - epidemiology Thrombosis - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!