Effects of arachidonic acid metabolites in a murine model of squamous cell carcinoma

Background A murine model (C3H mice) of squamous cell carcinoma (SCCVII) has been used to investigate the role of arachidonic acid (AA) metabolites in head and neck cancer. Inhibition of tumor growth by cyclooxygenase (COX) and lipoxygenase (LOX) inhibitors of AA metabolism has been associated with...

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Veröffentlicht in:	Head & neck 2000-03, Vol.22 (2), p.149-155
Hauptverfasser:	Scioscia, Kenneth A., Snyderman, Carl H., D'Amico, Frank, Comsa, Seia, Rueger, Robert, Light, Benjamin
Format:	Artikel
Sprache:	eng
Schlagworte:	12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - administration & dosage Analysis Animals arachidonic acid Arachidonic Acids - metabolism Biological and medical sciences carcinoma Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - metabolism Cell Division - drug effects Cells, Cultured Dinoprostone - administration & dosage Disease Models, Animal Enzyme-Linked Immunosorbent Assay Female General pharmacology head and neck cancer Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - metabolism Injections, Intralesional Leukotriene B4 - administration & dosage Medical sciences Mice Mice, Inbred C3H Pharmacology. Drug treatments prostaglandins Reference Values squamous cell carcinoma
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