Langerhans cells acquire a CD8+ dendritic cell phenotype on maturation by CD40 ligation

Dendritic cell (DC) reconstitution experiments and phenotypic analysis of DC subpopu‐lations have allowed the definition in the mouse of two main DC categories: CD8+ lymphoid DCs and CD8− myeloid DCs. With regard to Langerhans cells (LCs), which represent immature DCs differentiating into mature DCs...

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Veröffentlicht in:	Journal of leukocyte biology 2000-02, Vol.67 (2), p.206-209
Hauptverfasser:	Anjuere, Fabienne, del Hoyo, Gloria Martínez, Martín, Pilar, Ardavín, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD40 Antigens - physiology CD40 Ligand CD8 Antigens - analysis Cell Differentiation Dendritic Cells - classification Dendritic Cells - cytology Epidermal Cells Epidermis - immunology Female Flow Cytometry Langerhans Cells - cytology Langerhans Cells - metabolism lymphoid dendritic cells Membrane Glycoproteins - physiology Mice Mice, Inbred BALB C Protein Binding skin Skin - cytology Skin - immunology
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