Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study

Glutathione S-transferases (GSTs) have been associated with outcome in human cancers treated with cytotoxic chemotherapy. In a case-control study, we investigated the association between polymorphisms within theGSTM1, GSTT1, and GSTP1 genes and risk of relapse in childhood acute lymphoblastic leukem...

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Veröffentlicht in:	Blood 2000-02, Vol.95 (4), p.1222-1228
Hauptverfasser:	Stanulla, Martin, Schrappe, Martin, Brechlin, Annette Müller, Zimmermann, Martin, Welte, Karl
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bone Marrow - pathology Burkitt Lymphoma - drug therapy Burkitt Lymphoma - genetics Case-Control Studies Child Child, Preschool Female Follow-Up Studies Glutathione S-Transferase pi Glutathione Transferase - genetics Hematologic and hematopoietic diseases Humans Infant Isoenzymes - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Polymorphism, Genetic Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Preleukemia - drug therapy Preleukemia - genetics Recurrence Remission Induction Risk Factors Time Factors
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