An Array of Positioned Nucleosomes Potentiates Thyroid Hormone Receptor Action in Vivo

The assembly of the genome into chromatin imposes a poorly understood set of rules and constraints on action by regulatory factors. We investigated the role played by chromatin infrastructure in enabling an acute response of the XenopusTRβA gene to thyroid hormone receptor (TR), an extensively studi...

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Veröffentlicht in:	The Journal of biological chemistry 2001-06, Vol.276 (23), p.19753-19761
Hauptverfasser:	Urnov, Fyodor D., Wolffe, Alan P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence DNA Enhancer Elements, Genetic Molecular Sequence Data Nucleosomes - physiology Promoter Regions, Genetic Protein Binding Receptors, Thyroid Hormone - genetics Receptors, Thyroid Hormone - metabolism Receptors, Thyroid Hormone - physiology TR^bA gene Triiodothyronine - physiology Xenopus
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