Overexpression of parathyroid hormone-related protein promotes cell growth in the rat intestinal cell line IEC-6

The rat intestinal cell line, IEC-6, was used as a model to study effects of parathyroid hormone-related protein (PTHrP) on crypt cell growth. Studies showed that addition of PTHrP analogs (1–34), (67–86), or (107–139) to growth medium did not affect proliferation of cells grown in either high (10%...

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Veröffentlicht in:	Regulatory peptides 2001-06, Vol.99 (2), p.169-174
Hauptverfasser:	Ye, Yumei, Falzon, Miriam, Seitz, Patricia K, Cooper, Cary W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Division - genetics Cell Line Fundamental and applied biological sciences. Psychology Genetic Vectors - chemical synthesis GI epithelium Humans Intestine. Mesentery Nuclear localization signal Nuclear Localization Signals - genetics Parathyroid Hormone-Related Protein Peptide Fragments - pharmacology Protein Biosynthesis Proteins - genetics Proteins - pharmacology Proteins - physiology Rats Sequence Deletion - genetics Transfection Vertebrates: digestive system
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