Functional conservation of atonal and Math1 in the CNS and PNS

To determine the extent to which atonal and its mouse homolog Math1 exhibit functional conservation, we inserted (beta)-galactosidase (lacZ) into the Math1 locus and analyzed its expression, evaluated consequences of loss of Math1 function, and expressed Math1 in atonal mutant flies. lacZ under the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Development (Cambridge) 2000-03, Vol.127 (5), p.1039-1048
Hauptverfasser:	Ben-Arie, N., Hassan, B. A., Bermingham, N. A., Malicki, D. M., Armstrong, D., Matzuk, M., Bellen, H. J., Zoghbi, H. Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals atonal gene Basic Helix-Loop-Helix Transcription Factors beta-Galactosidase - analysis beta-Galactosidase - genetics Central Nervous System - embryology DNA-Binding Proteins - genetics Drosophila Drosophila - embryology Drosophila Proteins Embryo, Nonmammalian - embryology Female Gene Expression Regulation, Developmental Helix-Loop-Helix Motifs lacZ gene Life Sciences (General) Male Math1 gene Mice Mice, Transgenic Nerve Tissue Proteins - genetics Organ Specificity Peripheral Nervous System - embryology Transcription Factors - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!