Inhibitor of neurite outgrowth in humans

Axons are generally believed to be incapable of regeneration in the adult central nervous system. Inhibition results from physical barriers imposed by glial scars, a lack of neurotrophic factors, and growth-inhibitory molecules associated with myelin, the insulating axon sheath. These molecules incl...

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Veröffentlicht in:	Nature (London) 2000-01, Vol.403 (6768), p.383-384
Hauptverfasser:	PRINJHA, R, MOORE, S. E, VINSON, M, BLAKE, S, MORROW, R, CHRISTIE, G, MICHALOVICH, D, SIMMONS, D. L, WALSH, F. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cattle Development. Senescence. Regeneration. Transplantation Fundamental and applied biological sciences. Psychology Growth Inhibitors - genetics Growth Inhibitors - physiology Humans In Vitro Techniques Membrane Proteins - genetics Membrane Proteins - physiology Molecular Sequence Data Myelin Proteins - genetics Myelin Proteins - physiology Nerve Regeneration Neurites - physiology Nogo protein Nogo Proteins Protein Isoforms Vertebrates: nervous system and sense organs
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