A Comparison of Sodium Hydroxide and Sodium Sulfide Digestion of Mouse Hair in the Recovery of Radioactivity Following Systemic Administration of [3H]-Nicotine and [3H]-Flunitrazepam

Pigmented (C57Bl) and nonpigmented (balb/c) mice, 25 days of age, were treated intraperitoneally with [3H]-nicotine (4 mg/kg, 555 dpm/ng) or [3H]-flunitrazepam (1 mg/kg, 2200 dpm/ng) daily for three days. After 21 days, shaved back hair was digested at 37°C for 24 h with either 1M sodium hydroxide o...

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